DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and MFS18

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	118/472 - (25%)
Similarity:	212/472 - (44%)	Gaps:	54/472 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MDMEAKNSNKEDEAVGKHSGLGVRHFQ---VLLLFFALTVAYGCRVNLSVAVVAMTDAASVNPDF 74
            ||.:.|.|....|.|...| :..||.:   .:.|.....:.|..|..:.:.|.|:..|
  Fly     1 MDEKLKYSLLRGELVDTQS-IWTRHEKRVWFITLITGTCMLYSTRTTMPLLVPAVASA------- 57

  Fly    75 PEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGG-- 137
              ..||:.....:||||||||.:|||..|..:.::||:.:||......|::..|.|......|
  Fly    58 --QKWSKTDSGTVLSSFFWGYTLTQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPTIIWTAGSI 120

  Fly   138 ----WQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIA 198
                ...:.|:|::.|..|||.|||..::.||...|.||::......:|:..||:|    :|::.
  Fly   121 KSYAIPFIVAIRILNGALQGVHFPSMISLTSQNLCPNERSSFFGLLTAGSALGTLL----TGIMG 181

  Fly   199 A---SPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQPK 260
            :   ...||..:|.:.|.:|..|::|..::         :::.|..::|.::....:. ..:.|.
  Fly   182 SFLLDYFGWSYVFRVIGLMGIAWALVLRYY---------AMAGERNRIINIATPSRLC-ANKSPA 236

  Fly   261 EQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFA 325
            |....|||.:|...:|...:::|:.....|:.||:.:|:|..:  |.......:::.:|::.:..
  Fly   237 ETSAVPWLRYFRRLSFWACVLTHACEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWLALPP 299

  Fly   326 MSFVFSSISAQLNNRNCISRSTSRKLFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNG 390
            .:.....::.:|..|.. ..:|.||:..|.......:.|    :|....|:....|:|.|:.:.|
  Fly   300 CTLFAKYLTTRLLAREW-HTTTVRKVIQSCCFAAQNLAL----FVMSRTSDFHTALICMTIIIGG 359

  Fly   391 ATYLGFNTNHI-----DLSPNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIA 450
            .   ||:.|.:     ||:|..:|.:.|:.|.|..|...:...:.|.|:   ...:.|.:||..|
  Fly   360 T---GFHNNAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHIL---ELTQSWPMVFSAA 418

  Fly   451 AGFYLVGNTLYVIFGKA 467
            ||..|||..::::||.|
  Fly   419 AGINLVGWIIFIVFGSA 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	111/449 (25%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	106/437 (24%)
MFS18	NP_608835.1	MFS	30..432	CDD:119392	106/437 (24%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	95/397 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451993
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	1	0.950	-	0	Normalized mean entropy	S4312
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.840