DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and MFS3

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	171/519 - (32%)
Similarity:	261/519 - (50%)	Gaps:	68/519 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DEAVGKHSGLG----VRHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAASV-------------- 70
            ||...|.|.||    .|:...||....:.:.||.:||||||:|||.:..::
  Fly     3 DEVPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGS 67

  Fly    71 ---------------NP------------DFPEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARK 108
                           ||            |.| ::|||..:..|||.:||||:::|:|...:|..
  Fly    68 VILSNASQVSLVEECNPPGGASNVTAKVEDGP-FDWSEPLQGTLLSCYFWGYLVSQIPLAHVAEN 131

  Fly   109 YGGKVMILSGLAICSILNILTPICAKI--GGWQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKE 171
            :..|.::|..:||..:..:|||:..::  ||   :..:||:||:..|..||:.|.:::.||||.|
  Fly   132 FSAKWVMLFSVAINVVCTLLTPVFTELHYGG---LILMRVLEGVGGGASFPAMHVMIASWAPPTE 193

  Fly   172 RATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSI 236
            |..:.|..|.|...||.|.:..:||.:|. .||.|:||:.|.:.|:|.:::......:|.:.:.|
  Fly   194 RMVMSTIIYVGTSAGTALSILLAGVCSAQ-WGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFI 257

  Fly   237 SAEEKKLIEMSQADEVSGGQEQPKEQLP-TPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSY 300
            |.||:::|..|.      |.||..|..| .||...|||..|..::::|:..|:|::..|.|||.|
  Fly   258 SLEERQMITSSL------GTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFY 316

  Fly   301 MKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIGLWIPMVTLV 365
            ||.:|..::.|||.||:|||..|...|.....:...|..:..|:.:.:||...||...||.|.|:
  Fly   317 MKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLL 381

  Fly   366 GLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVANIMSIIAPLIV 430
            .|.|:.....|...|:....|.| |:.:.||.:||||::|||||.|:.:||..|.:..|:.||.|
  Fly   382 VLCYIGCRHYEAVSVMSVGIVAM-GSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFV 445

  Fly   431 GFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWN------DPPAKPRRNSTPQVE 488
            ||:.....:...|||:|.:....:.:...::|..|..:.||||      ||.||..:  ||..|
  Fly   446 GFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKDPEAKDEK--TPLKE 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	162/493 (33%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	152/467 (33%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	157/481 (33%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	135/389 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970