DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15096 and Slc17a3

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_006254003.1	Gene:	Slc17a3 / 266730	RGDID:	628815	Length:	538	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	136/467 - (29%)
Similarity:	223/467 - (47%)	Gaps:	50/467 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VAYGCRVNL-------SVAVVAM---TDAAS------------VNPD-----------FPEYNWS 80
            :|:.|...|       |:.:|||   ||..|            :|.|           .|.||||
  Rat    84 IAHICNFTLIAQNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKAPVYNWS 148

  Fly    81 EKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALR 145
            .:|:.::.||..:|.::.|.|.|.||.|.|.|.::...|...|:|.:..|:.|.: |...:.|.|
  Rat   149 PQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSLLTLCIPLAANL-GLAFLLATR 212

  Fly   146 VVEGLCQGVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYI 210
            .|:||.||..:.....:..:||||.||:.|.:.|.||...|...:|...|:|:.: :|||.:|||
  Rat   213 AVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVLLVGGIISEA-LGWPFVFYI 276

  Fly   211 SGGIGCVWSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQPKEQLPTPWLSFFTSPA 275
            .|.||.|..:::.......|.....||:.||:.| :|..|:....:||     |.|..:...|..
  Rat   277 FGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYI-LSSLDQQFNSEEQ-----PLPIKAMLKSLP 335

  Fly   276 FLVLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNR 340
            ...:.:....|.|...||:...|:|:.::...:|:.|.||||||:...:.:..:...::..|.::
  Rat   336 LWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILGGLLADFLLSK 400

  Fly   341 NCISRSTSRKLFNSIGLWIPMVTLVGLGYVNPDQSELA-VVLLCFTVGMNGATYLGFNTNHIDLS 404
            | ....|.||:...:|...|...:|.|.||  ..|.:| ...|..:.|::.....|...|.:|::
  Rat   401 N-FRLITVRKIITILGNTPPAALVVALPYV--QSSYIATTTFLTLSCGLSPLCQSGVYINALDIA 462

  Fly   405 PNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANV 469
            |.:|.:|||.:.|:|:..:::.|::.||.: |:.....||..||:.....|.|..:|::|.||::
  Rat   463 PRYASLLMGTSRGLAHSSAVMVPIVAGFFL-NQDSEFGWRNFFFVLFAINLFGLIIYLVFAKADI 526

  Fly   470 QPWNDPPAKPRR 481
            |.|    |:.|:
  Rat   527 QEW----ARERK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	135/464 (29%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	129/448 (29%)
Slc17a3	XP_006254003.1	2A0114euk	71..537	CDD:129972	136/467 (29%)
Slc17a3	XP_006254003.1	MFS	145..522	CDD:119392	116/388 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750