DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15096 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	505	Identity:	109/505 - (21%)
Similarity:	188/505 - (37%)	Gaps:	115/505 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SNGTMDMEAKNSNKEDEAVGKHSGLGVRHFQVL------LLFFALTVAYGCRVNLSVA------- 60
            |||::..:|..|.|........|.:.:.:..:.      |||         |::|.:|
pombe    12 SNGSIFTKADESEKVISRSNTASPISIENTHLTKSERDSLLF---------RLDLVLAPTIMILY 67

  Fly    61 VVAMTDAASVN----PDFPEYNWSEKTK----SLLLSSFFWGYVITQVPAGQLARKYGGKVMILS 117
            :||..|.:::.    ...||   ..|.|    :::.|.|:..:::.::|...|.:|...|.|:..
pombe    68 LVAFLDRSNIGNAKVAGLPE---DLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAF 129

  Fly   118 GLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHTILSQ-----WAPPKERATLGT 177
            .:...|:..|.|..|...||   :.|.|:|.|.|:..:||.....|:.     ...|:......:
pombe   130 IVISYSLTTIFTGFCHNFGG---LLAARLVLGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFAS 191

  Fly   178 CAYSGNQFGTIL---MLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSISAE 239
            .|.|| .||.:.   :|...||  ....||..:|.|.|.||.|..|..:|.......:...:|..
pombe   192 SALSG-AFGGLFAYAVLHMDGV--GGFAGWRWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKT 253

  Fly   240 EKKLIEMSQADEVSGGQEQPKEQLPTPW---LSFFTSPAFLVLIVSHSVHN-----WGFWTLLTE 296
            .::::...|.:..:     ..|.....|   .|.||.  |.|.:.:.|...     :||.|.|..
pombe   254 HQEMMRKRQLERAA-----DLEAAHFDWKGVKSAFTD--FKVYLYALSEFGQDTCLYGFSTFLPA 311

  Fly   297 IPSYMKNILGKDIKS-NALLSSLPYVCMFAMSFVFSS-ISAQLNNRNCISRSTSRKLFNSIGLWI 359
            |      |.|....| :....::|...:.|.:::.:| :|.:.::|..|.         .||...
pombe   312 I------ISGMGYTSLSVQYMTIPVYILGAATYIAASFLSDRFHHRGIIL---------IIGNIF 361

  Fly   360 PMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFA---------------- 408
            |:|..:.|.....::|.|.......:||:    |.|...|...||.|.|
pombe   362 PIVGYILLLACQNNKSVLYFACYLCSVGV----YTGAGLNVTWLSANIAPHYKRATAISLQLAIA 422

  Fly   409 ---GILMG-------------ITNGVANIMSIIAPLIVGFIVTNEHDPEQ 442
               |||.|             :|:.:|..:|.:..::..|.:.:::..:|
pombe   423 NSSGILAGQIYRYPPKYIAGHLTSLIAIFISTVLHVVNIFFLKHQNSKKQ 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	102/478 (21%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	102/474 (22%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	94/426 (22%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	91/404 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050