DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	481	Identity:	101/481 - (20%)
Similarity:	188/481 - (39%)	Gaps:	115/481 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SNGTMD------MEAKN----SNKEDEAVGKHSGLGVR---HFQVLLLFFAL-TVAYGCRVNLSV 59
            ||..:|      .|||:    :.|:|:.        :|   :|.||::...| .:.|..:..||.
pombe    53 SNAVLDETFSFMQEAKDLEPLTPKQDKR--------LRWKLYFTVLVMLMILDMMLYIDKATLSY 109

  Fly    60 -AVVAMTDAASVNPDFPEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICS 123
             :::.:.:...:|.:  :||       .:.:.|:.|:||.|:|...|.:::.....:.:..|:.:
pombe   110 SSILGLFEDTHINSN--QYN-------DINTLFYVGFVIGQIPGHMLLQRFPVSKFVAASTALWT 165

  Fly   124 ILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKERATL------------- 175
            |:..|........|   :.|||...||.:..:.|:....:..:.|..|:|.|
pombe   166 IIIFLHCAAYNFSG---LMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNI 227

  Fly   176 --GTCAYSGNQF--GTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSI 236
              |..|| |.|:  .||           ||  |.....|.|||....::..||:...:....:.:
pombe   228 PAGFIAY-GVQYAKNTI-----------SP--WKLFMIIVGGITFFLTIGLFFYYPDNTSTARFL 278

  Fly   237 SAEEK-KLIEMSQADEVSGGQEQ--PKEQL------PTPWLSFFTSPAFLVLIVSHSVHNWGFWT 292
            :.:|: ..::..:....||.:.:  .|.|:      |..||  ||   |.|           |..
pombe   279 TKKERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTWL--FT---FHV-----------FCN 327

  Fly   293 LLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIGL 357
            .|:...:|.:|:|...:..:.|.|:|..|.....:.|.:.|:..:     :|...::..|:....
pombe   328 QLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYM-----MSVIKNQSAFHGAIW 387

  Fly   358 WIPMVTLVGLGYV----NPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGV 418
            :||.:. .|:..|    :....|||.:::....|:.....||:.|      .:.||....:|.||
pombe   388 YIPSIA-GGIACVAMSWDHKIGELAAIIIASNFGIPFIISLGWTT------ASCAGYTKKLTRGV 445

  Fly   419 ANIMSIIAPLIVGFIVTNEHDPEQWR 444
            .        .::|:.:.|...|:.|:
pombe   446 M--------FMIGYAIANIIGPQMWQ 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	93/444 (21%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	91/437 (21%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	90/436 (21%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	88/425 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050