DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	508	Identity:	150/508 - (29%)
Similarity:	254/508 - (50%)	Gaps:	47/508 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GGSNGTMDMEAKNSNKEDEAVGKHS---------------------------------GLGVRHF 38
            |.|.|.:..:...:|:|::|:..:.                                 |:..|:.
Mouse    26 GDSLGILQRKIDGTNEEEDAIELNEEGRPVQTSRAHRPVCDCSCCGIPKRYICDCSCCGIPKRYI 90

  Fly    39 QVLLLFFALTVAYGCRVNLSVAVVAMTDAASVNPD-FPE-----YNWSEKTKSLLLSSFFWGYVI 97
            ..::......:::|.|.||.||:|.|.:.::|..| .||     :||..:|..|:..||||||::
Mouse    91 IAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIV 155

  Fly    98 TQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHTI 162
            ||:|.|.::.|:....:..:.:.:.|.||:..|..|:: .:..|..:|:::||.:||.:|:.|.:
Mouse   156 TQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARV-HYGCVMGVRILQGLVEGVTYPACHGM 219

  Fly   163 LSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGA 227
            .|:||||.||:.|.|.::.|:..|.::.:..:||: ...|||.|:|||.|..|.:|.:.:.....
Mouse   220 WSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVL-VQYIGWASVFYIYGMFGIIWYMFWLLQAY 283

  Fly   228 GSPQECKSISAEEKKLIEMSQADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWT 292
            ..|....:||..|:..||.|..:   |.......:..|||..||||.....:||::...:|.|:.
Mouse   284 ECPAAHPTISNAERTYIETSIGE---GANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYL 345

  Fly   293 LLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIGL 357
            ||...|:|.:.:.|..|....|||::|::.|..:..:...::..|.:|..::.:..||:.|..|.
Mouse   346 LLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGF 410

  Fly   358 WIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVANIM 422
            .:....|:.:|:.:  ...:|:..|...||.:|....|||.||:|::|.:|.|||||:|||..:.
Mouse   411 GMEATLLLVVGFSH--TKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLS 473

  Fly   423 SIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDP 475
            .::.||||| .:|.....|:|:.||.|||..:..|...|.:|.....|.|.||
Mouse   474 GMVCPLIVG-AMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	143/446 (32%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	137/429 (32%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	143/446 (32%)
		MFS	93..515	CDD:119392	137/429 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830