DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and T22F3.7

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001309505.1	Gene:	T22F3.7 / 188751	WormBaseID:	WBGene00020697	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	479	Identity:	108/479 - (22%)
Similarity:	196/479 - (40%)	Gaps:	69/479 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VLLLFFALTVAYGCRVNLSVAVVAMTDAASVNPDFPE--------YNWSEKTKSLLLSSFFWGYV 96
            ::||...|.:|..|...|.:....:.....::..|.|        |:::.|.|:.::.|...|.:
Worm    10 IVLLIGFLCLASLCSNYLIINFTFICMKHDLSDGFTEINGTKYSIYDYTSKDKTWIIWSVAAGTI 74

  Fly    97 ITQVPAGQLARKYGGKV-MILSGLAICSILNILTPICAKIGGWQ--LVCALRVVEGLCQGVVFPS 158
            |..:|...:..|||.:: .:::||..| |...|.|:.|:   |.  .:..||.|:|.|....|.:
Worm    75 IGTIPLNMMYVKYGARIPFLIAGLVSC-IATALIPLSAQ---WNFFFLIFLRFVQGFCYSADFAA 135

  Fly   159 THTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCV----WS 219
            ...:..:|||..|.|.........|...:......:|:|..|.:||...:|:...:|.|    |.
Worm   136 IGLMTVRWAPLSETALFVAVLTCFNGIASTFTNFATGLICESSLGWKWAYYVHAIVGFVLFGLWL 200

  Fly   220 VVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSHS 284
            :||.    ..|||.|.:|.:|.:.|:.:::      :....::...|::...|||..|.:
Worm   201 LVYI----DHPQETKRVSRKELQKIQKNKS------EAHLSKKCDVPYMKLVTSPVILCV----- 250

  Fly   285 VHNW--GFWTLL------TEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRN 341
               |  .|:.|.      |.||.|:..:|...:......:||.......:.|||:.||.:|   .
Worm   251 ---WANAFFELTAAIMFSTYIPLYLHEVLKFGVTETGFYASLILGISLPVRFVFALISDKL---K 309

  Fly   342 CISRSTSRKLFNSIGLWIPMVTLVGLGYV---NPDQSELAVVLLCFTVGMNGATYLGFNTNHIDL 403
            .:|.......||:|.:.:..:....:|::   |...|....::....:|:|..   ||..:.:..
Worm   310 FVSEIFKIHTFNTISVGLSGLFFACIGFIPMENRGWSLFFCIMTMCCIGVNSG---GFYKSGVLH 371

  Fly   404 SPNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGN--TLYVIFGK 466
            |..|:.:::.....:..:...:||.:|...|..|.:..||..||.|..|..::.|  ..:::
Worm   372 SRQFSHVVITAIQWMKCLALFVAPALVSIFVHEESNRLQWIWVFLIVGGLMIITNIVAFFIL--- 433

  Fly   467 ANVQPWNDPPAKPRRNSTPQVESQ 490
                  .|.||    :.|..:||:
Worm   434 ------TDKPA----SWTGSLESE 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	105/467 (22%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	102/451 (23%)
T22F3.7	NP_001309505.1	MFS	10..428	CDD:391944	102/445 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810