DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15096 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	145/456 - (31%)
Similarity:	220/456 - (48%)	Gaps:	35/456 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAA--------SV-----NPDFPEYNWSEKTKSLL 87
            |:...:||.|...|....||.|::.:|||.:..        ||     |...|.::||...:.|:
  Rat    17 RYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLI 81

  Fly    88 LSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQ 152
            |||.|.|.|:.|||.|.|:..|..|.:|.|.|.:.|:|::|.|..|::|. .||...||::|:.|
  Rat    82 LSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGA-ALVIVCRVLQGIAQ 145

  Fly   153 GVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCV 217
            |.|....|.|..:||||.||..|.:...||...|..:.|..||.| ...:|||.:|||.|.:|||
  Rat   146 GAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFI-CDLLGWPMVFYIFGIVGCV 209

  Fly   218 WSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEV-SGGQEQP----KEQLPTPWLSFFTSPAFL 277
            .|:.:|......|.....:|:.||..|..|...:| ||.|..|    .:.||. |.....|.||:
  Rat   210 LSLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQSLPIKAMLKSLPL-WAIILNSFAFI 273

  Fly   278 VLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNC 342
                      |....|:|..|:::...|..:::.|.|||||||:..:....|...:|..|.:|..
  Rat   274 ----------WSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKI 328

  Fly   343 ISRSTSRKLFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNF 407
            .|....||||.::|::.|::.:|.|.|::.:... .|:.|.........::.|...|.:|::|.:
  Rat   329 FSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYS-TVIFLTLANSTLSFSFCGQLINALDIAPRY 392

  Fly   408 AGILMGITNGVANIMSIIAPLIVGFIVTNEHDPE-QWRIVFFIAAGFYLVGNTLYVIFGKANVQP 471
            .|.|..:|..:.....:|:..:.|.|:  ..||| .|...||:.||..:.....|::|.|.::|.
  Rat   393 YGFLKAVTALIGIFGGLISSTLAGLIL--NQDPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQD 455

  Fly   472 W 472
            |
  Rat   456 W 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	145/456 (32%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	140/442 (32%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	145/456 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910