DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15096 and Slc37a4

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001344658.1	Gene:	Slc37a4 / 14385	MGIID:	1316650	Length:	450	Species:	Mus musculus

Alignment Length:	504	Identity:	97/504 - (19%)
Similarity:	173/504 - (34%)	Gaps:	136/504 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GVRHFQVLL---LFFALTVAYGCRVNLSVAVVAMTDAASVNPDFPEYNWSEKTKSLLLSSFFWGY 95
            |..:::.::   :|...::.|..|...|..:.::.|..:::.|         ...|:.||....|
Mouse     5 GYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKD---------DLGLITSSQSAAY 60

  Fly    96 VITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTH 160
            .|::..:|.|:.:...:.:..|||.:..::|::....:.:..:   .||..:.||.||:.:|...
Mouse    61 AISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSAF---AALWFLNGLAQGLGWPPCG 122

  Fly   161 TILSQWAPPKERAT----LGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVV 221
            .||.:|..|.:..|    |.|........|.||     ..|.|....|.|...:||.: ||  ||
Mouse   123 KILRKWFEPSQFGTWWAVLSTSMNLAGSLGPIL-----ATILAQSYSWRSTLALSGAL-CV--VV 179

  Fly   222 YFFFGAGSPQECKSISAEEKKLIEMSQADEV--SGGQEQPKEQ------LPTPWLSFFTSPAFLV 278
            .||        |..:...|...:.:...|..  .|.:...||:      |.:|:|...::...:|
Mouse   180 SFF--------CLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVV 236

  Fly   279 LIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCI 343
            ..|.....:||.:.|:.|             :..:.|....|:....:..:..||:|...:...:
Mouse   237 FGVKTCCTDWGQFFLIQE-------------RGQSALVGSSYISALEVGGLVGSIAAGYLSDRAM 288

  Fly   344 SRSTSRKLFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYL-------------- 394
            :::         ||.:         |.||...    :||....||..:.:|
Mouse   289 AKA---------GLSL---------YGNPRHG----LLLLMMAGMAASMFLFRVTVTSDSPKDAF 331

  Fly   395 ------------GFNTNHI--------------------------DLSPNFAGILMGITNGVANI 421
                        ||..:.|                          ...||..|....|...:||:
Mouse   332 WTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANV 396

  Fly   422 MSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQ 470
            ...:|.|  .|....:|  ..|...|::|.  .:.|.:..|.|...|::
Mouse   397 GGFLAGL--PFSTIAKH--YSWSTAFWVAE--VVCGASTVVFFLLRNIR 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	96/502 (19%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	94/490 (19%)
Slc37a4	NP_001344658.1	MFS_SLC37A4	10..438	CDD:340901	95/496 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838765
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840