DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	475	Identity:	151/475 - (31%)
Similarity:	244/475 - (51%)	Gaps:	38/475 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GLGVRHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAA---------------------SVNP--- 72
            ||..|:...::......:::|.|.||.||:|:|.:.:                     :|.|
  Rat    58 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTPTVG 122

  Fly    73 -------DFPEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTP 130
                   :..::||..:|..|:..||||||::||:|.|.:.:|:....:....:...|.||:|.|
  Rat   123 DIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIP 187

  Fly   131 ICAKIGGWQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSG 195
            ..|:: .:..|..:|:::||.:||.:|:.|.|.|:||||.||:.|.|.|:.|:..|.::.:..:|
  Rat   188 SAARV-HYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAG 251

  Fly   196 VIAASPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQPK 260
            |:.... ||.|:||:.|..|..|.:.:......||....|||.||:|.||  .|...|.....|.
  Rat   252 VLVQYS-GWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIE--DAIGESAKLMNPV 313

  Fly   261 EQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFA 325
            .:..|||..||||.....:||::...:|.|:.||...|:|.:.:.|.:|....|:|:||::.|..
  Rat   314 TKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTI 378

  Fly   326 MSFVFSSISAQLNNRNCISRSTSRKLFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNG 390
            :..:...|:..|.:|:.:|.:..|||.|..|..:....|:.:||.:  ...:|:..|...||.:|
  Rat   379 IVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSH--SKGVAISFLVLAVGFSG 441

  Fly   391 ATYLGFNTNHIDLSPNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYL 455
            ....|||.||:|::|.:|.|||||:|||..:..::.|:||| .:|.....|:|:.||.||:..:.
  Rat   442 FAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVG-AMTKHKTREEWQYVFLIASLVHY 505

  Fly   456 VGNTLYVIFGKANVQPWNDP 475
            .|...|.:|.....|||.:|
  Rat   506 GGVIFYGVFASGEKQPWAEP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	149/471 (32%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	143/454 (31%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	143/455 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342464
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860