DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and slc17a6

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_004913390.1	Gene:	slc17a6 / 101730310	XenbaseID:	XB-GENE-1011394	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	452	Identity:	146/452 - (32%)
Similarity:	248/452 - (54%)	Gaps:	17/452 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GLGVRHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAASVN------PDFPEYNWSEKTKSLLLSS 90
            ||..|:...::......:::|.|.||.||:|.|.:.::::      .:..::||..:...::..|
Frog    66 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHHGGKIIKEKAKFNWDPEIVGMIHGS 130

  Fly    91 FFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVV 155
            |||||::||:|.|.:|.:.....:..:.:.:.|.||:|.|..|:: .:..|..:|:::||.:||.
Frog   131 FFWGYIVTQIPGGYIASRLAANRVFGAAIVLTSTLNMLIPSAARV-HYGCVIFVRILQGLVEGVT 194

  Fly   156 FPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSV 220
            :|:.|.|.|:||||.||:.|.|.::.|:..|.::.:..:|:: ....||.|:||:.|..|.||.:
Frog   195 YPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGIL-VQYTGWSSVFYVYGCFGLVWYL 258

  Fly   221 VYFFFGAGSPQECKSISAEEKKLIEMS--QADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSH 283
            .:......||.:..:|:.||:..||.|  ::..:.|    |.|:..|||..||||.....:||::
Frog   259 FWILVSYESPAKHPTITDEERNYIEESIGESANILG----PVEKFKTPWRKFFTSMPVYAIIVAN 319

  Fly   284 SVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTS 348
            ...:|.|:.||...|:|.:.:.|.:|....:||::|::.|..:..:...|:..|.::..:|.:|.
Frog   320 FCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTV 384

  Fly   349 RKLFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMG 413
            ||:.|..|..:....|:.:||.:  ...:|:..|...||.:|....|||.||:|::|.:|.||||
Frog   385 RKIMNCGGFGMEATLLLVVGYSH--SKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMG 447

  Fly   414 ITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDP 475
            |:|||..:..::.||||| .:|.....|:|:.||.|||..:..|...|.||.....|||.||
Frog   448 ISNGVGTLSGMVCPLIVG-AMTKHKSREEWQYVFLIAALVHYGGVIFYGIFASGEKQPWADP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	144/448 (32%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	136/431 (32%)
slc17a6	XP_004913390.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	137/432 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11242
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010