DRSC/TRiP Functional Genomics Resources

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Protein Alignment JAK2 and YPL162C

DIOPT Version :10

Sequence 1:NP_004963.1 Gene:JAK2 / 3717 HGNCID:6192 Length:1132 Species:Homo sapiens
Sequence 2:NP_015163.1 Gene:YPL162C / 855941 SGDID:S000006083 Length:273 Species:Saccharomyces cerevisiae


Alignment Length:42 Identity:12/42 - (28%)
Similarity:22/42 - (52%) Gaps:5/42 - (11%)


- Green bases have known domain annotations that are detailed below.


Human   303 HKESETLT-----EQDLQLYCDFPNIIDVSIKQANQEGSNES 339
            |.||.|:|     |.:..|..:.|::.:||.:..|::.:..|
Yeast   227 HSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISS 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
JAK2NP_004963.1 Interaction with cytokine/interferon/growth hormone receptors. /evidence=ECO:0000250 1..239
FERM_F1 39..134 CDD:465733
FERM_F2 143..261 CDD:436450
FERM_C_JAK2 266..386 CDD:270141 12/42 (29%)
SH2_Jak2 386..482 CDD:198242
PTK_Jak2_rpt1 545..806 CDD:270663
PTKc_Jak2_rpt2 844..1127 CDD:271107
YPL162CNP_015163.1 STIMATE 93..226 CDD:463561
Blue background indicates that the domain is not in the aligned region.

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