Protein Alignment MFS15 and FEN2

DIOPT Version :10

• Sequence 1: NP_611375.2
• Gene: MFS15 / 37168
• FlyBaseID: FBgn0034392
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_009957.1
• Gene: FEN2 / 850394
• SGDID: S000000623
• Length: 512
• Species: Saccharomyces cerevisiae
• Alignment Length: 429
• Identity: 92/429 - (21%)
• Similarity: 150/429 - (34%)
• Gaps: 123/429 - (28%)

  Fly    71 NESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGG------- 128
            |:.|.|..:  |..||:|..:|...:              |:|....:...||....|
Yeast    72 NDLTVSNTV--FMIGYIVGMVPNNLM--------------LLCVPPRIWLSFCTFAWGLLTLGMY 120

  Fly   129 ----WTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEE---------RGRLVGYTYSGSQFGTVV 180
                :..:..:|..|.|.:...|..||..|..|...:|         ...|||..:||. ..|.:
Yeast   121 KVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGF-MQTSI 184

  Fly   181 MLSVSGYIASSSLGWPSTFYIPGCVGI---VWSFVWLYLCSSTPAQHPTITP-NERRFIESSGQ- 240
            ...::|  .:...||...|.|..|:.:   ::.|::.   ...|.|...::. :..|:|.:..:
Yeast   185 FTHLNG--RNGLAGWRWLFIIDFCITLPIAIYGFIFF---PGLPDQTSAVSKFSMTRYIFNEQEL 244

  Fly   241 --ARRPSDAGREEQ--------PRPPTPW-WRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMK 294
              |||...| |:|.        ||....| |.:|:    ||.||.  ..|.||.:..|
Yeast   245 HYARRRLPA-RDESTRLDWSTIPRVLKRWHWWMFS----LVWVLG--GENLGFASNST------- 295

  Fly   295 NVLGMDIKNNGPLSALPYFAMILLTCVFIWLSD---TLKQRGTVIPLG-FSRKFFNTL--GMWLP 353
                              ||        :||.:   ||.||.. .|.| |:....:||  .:::.
Yeast   296 ------------------FA--------LWLQNQKYTLAQRNN-YPSGIFAVGIVSTLCSAVYMS 333

  Fly   354 MLALIGLGYITEGEANVRLAIGLLTAAVATN-----SATYLGFHVNHIDLSPNYAGTLMGIT--- 410
            .:......:::...:.|.:.:.:|..|...|     ||.|||        ...|||..:..:
Yeast   334 KIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVVFSAQYLG--------GVAYAGQAVFFSWAN 390

  Fly   411 -NCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFV 448
             .|.|:... .|.::..:.::.....|.|.|:||.:..|
Yeast   391 IICHADLQE-RAIVLASMNMFSGAVNAWWSILFFASDMV 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	MFS_SLC17	31..460	CDD:340876	92/429 (21%)
		PTZ00334	228..>281	CDD:240366	18/65 (28%)
FEN2	NP_009957.1	MFS_FEN2_like	32..450	CDD:340885	92/429 (21%)