DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and Slc17a6

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_445879.1	Gene:	Slc17a6 / 84487	RGDID:	620531	Length:	582	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	160/482 - (33%)
Similarity:	258/482 - (53%)	Gaps:	26/482 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FGV--RHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNASN------PDFPEFDWNESTKSYLLS 80
            ||:  |::..|:...|..:::.:|.||.||||.|.:.:..:      .:..:|:|:..|...:..
  Rat    65 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHG 129

  Fly    81 SFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCA-VNGGWTVVVVLRAVQGLCQG 144
            ||||||::|||||||:::...|..:....:|:.|.|.:|.|..| |:.|  .|:.:|.:|||.:|
  Rat   130 SFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG--CVIFVRILQGLVEG 192

  Fly   145 VIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVW 209
            |.:|:.|...|||||..||.||...::.||..|.|:.:.::|.:...: ||.|.||:.|..|:||
  Rat   193 VTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMVW 256

  Fly   210 SFVWLYLCSSTPAQHPTITPNERRFIESS-GQARRPSDAGREEQPRPPTPWWRIFTSVPFLVLVL 273
            ...||.:...:||:|||||..|||:||.| |::.....|    ..:..|||.:.|||:|...:::
  Rat   257 YMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGA----MEKFKTPWRKFFTSMPVYAIIV 317

  Fly   274 AHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGTVIPL 338
            |:...:|.|:.||...|.:.:.|.|.:|...|.|||:|:..|.::..:...::|.|:.: .::..
  Rat   318 ANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSK-QILST 381

  Fly   339 GFSRKFFNTLGMWLPMLALIGLGYI-TEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNY 402
            ...||..|..|..:....|:.:||. |.|     :||..|..||..:.....||:|||:|::|.|
  Rat   382 TTVRKIMNCGGFGMEATLLLVVGYSHTRG-----VAISFLVLAVGFSGFAISGFNVNHLDIAPRY 441

  Fly   403 AGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPW 467
            |..||||:|.......::.|:|||.:..:::. .:|:.||...|.|::.|.:.:.||.....|||
  Rat   442 ASILMGISNGVGTLSGMVCPIIVGAMTKNKSR-EEWQYVFLIAALVHYGGVIFYALFASGEKQPW 505

  Fly   468 NSRPTTRTPSPGGGGERDEGTEDRGPL 494
             :.|...:....|....||..|:.|.:
  Rat   506 -ADPEETSEEKCGFIHEDELDEETGDI 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	154/455 (34%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	146/436 (33%)
Slc17a6	NP_445879.1	2A0114euk	70..511	CDD:129972	153/455 (34%)
Slc17a6	NP_445879.1	MFS	75..498	CDD:119392	147/436 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830