DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and slc17a7a

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001092225.1	Gene:	slc17a7a / 795293	ZFINID:	ZDB-GENE-050105-5	Length:	582	Species:	Danio rerio

Alignment Length:	479	Identity:	164/479 - (34%)
Similarity:	250/479 - (52%)	Gaps:	29/479 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FGV--RHLQCILVFFGLAVAYSLRVNLSVAIVAM-TDRNASNPDFP-----EFDWNESTKSYLLS 80
            ||:  |::..||...|..:::.:|.||.||||:| .|....:...|     :|.|:..|...:..
Zfish    57 FGLPRRYIIAILSGLGFCISFGIRCNLGVAIVSMVNDHTVYSGKKPVIVAAQFTWDPETVGMIHG 121

  Fly    81 SFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCA-VNGGWTVVVVLRAVQGLCQG 144
            ||||||:|||||||::...:.|..:..:.::..|.|.:|.|..| |:.|  .|:::|..|||.:|
Zfish   122 SFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYG--CVIMVRVCQGLVEG 184

  Fly   145 VIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVW 209
            |.:|:.|...:||||..||.||....:.||..|.||.:.::|.:...: ||.|.||:.|.|||.|
Zfish   185 VSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYT-GWSSVFYVYGSVGIFW 248

  Fly   210 SFVWLYLCSSTPAQHPTITPNERRFIESS-GQARRPSDAGR-EEQPRPPTPWWRIFTSVPFLVLV 272
            ...|:.:...:||.||||||.||::||.: |::     ||. ....:..|||...|||:|...::
Zfish   249 YLFWILVSYESPAAHPTITPEERKYIEDAIGES-----AGLVNPLQKFKTPWRHFFTSMPVYAII 308

  Fly   273 LAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGTVIP 337
            :|:...:|.|:.||...|.:.:.|.|.:|...|.:||||:..|.::..:...|:|.|:....:..
Zfish   309 VANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRTHNLMTT 373

  Fly   338 LGFSRKFFNT--LGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSP 400
            ... ||..|.  .||...:|.::|..: |:|     :||..|..||..:.....||:|||:|::|
Zfish   374 TNV-RKLMNCGGFGMEATLLLVVGFSH-TKG-----VAISFLVLAVGFSGFAISGFNVNHLDIAP 431

  Fly   401 NYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQ 465
            .||..||||:|.......::.|||||.:...:|. .:|:.||...|.|::.|.:.:.||.....|
Zfish   432 RYASILMGISNGVGTLSGMVCPLIVGAMTKHKTR-EEWQYVFLIAALVHYGGVIFYGLFASGEKQ 495

  Fly   466 PWNSRPTTRTPSPGGGGERDEGTE 489
            ||.....|.....|..||.:...|
Zfish   496 PWADAENTSEEKCGILGEDELANE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	159/457 (35%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	151/438 (34%)
slc17a7a	NP_001092225.1	2A0114euk	62..501	CDD:129972	157/454 (35%)
slc17a7a	NP_001092225.1	MFS	67..490	CDD:119392	152/438 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.760