DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	497	Identity:	145/497 - (29%)
Similarity:	241/497 - (48%)	Gaps:	69/497 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CCNHNGYQQIGNTGPRFGVRH-LQCILVFFGLAVAYSLRVNLSVAIVAMTDRNAS---------- 61
            ||:               :|| |..||.....:| |:.::|||:||.||.:..|:
  Rat    32 CCS---------------LRHGLAFILHLCNFSV-YTQQMNLSIAITAMVNTTAASSHANASIER 80

  Fly    62 ----NPDF----------PEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLI 112
                :.||          |.:||....:..||||..:|..:..||.||::.::||||::..|:|:
  Rat    81 PTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYVVGLGLLV 145

  Fly   113 CSCLALLTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFG 177
            .|.|.|..|. |...|..:::|||.:||:.|.::....::..:||||..||.:|:....|||..|
  Rat   146 SSVLTLFIPL-AAEAGVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIAASGSMLG 209

  Fly   178 TVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQAR 242
            |.::| ::|.:...:||||..|||.|.:|.....:|..|....|..||.|:..|:|:|..| .|:
  Rat   210 TFLVL-IAGGLLCQALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKRYIMCS-LAQ 272

  Fly   243 RPSDAGREEQPRPPTPWWRI-----FTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIK 302
            .....|           |.:     ..|:|...:|:::....|..:|::...||::.:||..:::
  Rat   273 EDCSLG-----------WSLPIKAMVKSLPLWAIVVSYFCEYWLLFTIMAYTPTYISSVLQANLR 326

  Fly   303 NNGPLSALPYFAMILLTCVFI--WLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITE 365
            ::|.|||||:  |....|:.:  .|:|.|..| .::.|...||.|..||:.:....|:.|.:::
  Rat   327 DSGILSALPF--MFGCVCIILGGLLADFLLSR-NILRLVTIRKLFTALGVLVSSGILVPLPWVS- 387

  Fly   366 GEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVW 430
            ...:..:|..:|::..|  |....|..:|.:|::|.|||.|.|:....:.....:||.:.|..:
  Rat   388 SSLSTTMAFLVLSSVFA--SLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFI- 449

  Fly   431 DETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRPT 472
            .:.:...||.||...|.:..:|.|.:::|||..||.|...||
  Rat   450 SQDSEFGWRNVFLLAAAIDVVGLLFYLIFGRAEVQDWAKEPT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	141/482 (29%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	132/458 (29%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	132/460 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840