Protein Alignment MFS15 and SLC37A1

DIOPT Version :9

• Sequence 1: NP_611375.2
• Gene: MFS15 / 37168
• FlyBaseID: FBgn0034392
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_011527916.1
• Gene: SLC37A1 / 54020
• HGNCID: 11024
• Length: 577
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 109/457 - (23%)
• Similarity: 176/457 - (38%)
• Gaps: 105/457 - (22%)

  Fly    59 NASNPDFPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYG----AKYMLFYGVLICSCLALL 119
            |.::..:..||.|...:  ||.:..:.::.....|.|||.|.|    .:|.|.:|:|....
Human   112 NETDCGWAPFDKNNYQQ--LLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGA---- 170

  Fly   120 TPFCAVNG--------GWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQF 176
              |.|:.|        .:...||.:.:.||.|...:||..|.|..|.....||.::|...|.:..
Human   171 --FTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNSHTSV 233

  Fly   177 GTVVMLSVSGYIASSSLGWPSTFYIPGCV----GIVWSFVWLYL--------CSSTPAQH----- 224
            |.::...::||..|:.  |..:|.:||.:    |||   .:|:|        ||||...|
Human   234 GNILGSLIAGYWVSTC--WGLSFVVPGAIVAAMGIV---CFLFLIEHPNDVRCSSTLVTHSKGYE 293

  Fly   225 ------------------PTITPNERRFIESSGQAR--------RPSDAGREEQPRPPTPWWRIF 263
                              ..:.|..:..:.|.|:..        .|.|.|........|...:|.
Human   294 NGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKIP 358

  Fly   264 TSVPF-LVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSAL----PYFAMILLTCVFI 323
            ..:.| |.|:.|...:    :|.|..:|.::.||..:|.|..|.||.|    ..|..||...:
Human   359 GVIEFSLCLLFAKLVS----YTFLFWLPLYITNVDHLDAKKAGELSTLFDVGGIFGGILAGVI-- 417

  Fly   324 WLSDTLKQR----GTVIPLGFSRKF-FNT---LGMWLPMLALIGLGYITEGEANVRLAIGLLTAA 380
              ||.|::|    |.::.|.....: |:|   :|:...:..|:..|.:..|...      |:|.|
Human   418 --SDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYT------LITTA 474

  Fly   381 VATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFT 445
            |:.:..|:.....|...||     |:..|.:...:..:.|.||:.||:     :|:.|..||:..
Human   475 VSADLGTHKSLKGNAHALS-----TVTAIIDGTGSVGAALGPLLAGLL-----SPSGWSNVFYML 529

  Fly   446 AF 447
            .|
Human   530 MF 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	109/457 (24%)
		MFS	31..459	CDD:119392	109/457 (24%)
SLC37A1	XP_011527916.1	UhpC	51..543	CDD:225180	109/457 (24%)
		MFS	129..489	CDD:119392	90/384 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840