DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and slc37a1

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001007440.1	Gene:	slc37a1 / 492798	ZFINID:	ZDB-GENE-041114-151	Length:	529	Species:	Danio rerio

Alignment Length:	513	Identity:	113/513 - (22%)
Similarity:	190/513 - (37%)	Gaps:	118/513 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VAYSLRVNLSVAIVAMTDRNASNPD---FPEFD--W---NESTKSYLLSSFFWGYVVTQIPGGYL 96
            |...|..|.|.|:.|.|:.::|:..   .||||  |   :.:....||.:..:.::.....|.:|
Zfish    45 VKSELHKNCSHAVEAPTEISSSSQQPGHHPEFDCSWKPFDRNNYKQLLGAMDYSFLFAYAIGMFL 109

  Fly    97 SAIYG----AKYMLFYGVL---ICSCLALLTPFCAVNG-GWTVVVVLRAVQGLCQGVIFPSTHTF 153
            |.|.|    .:..|..|:|   :.:||..|.....::. |:.:.|  :...||.|...:||..|.
Zfish   110 SGIIGERLPIRLYLTVGMLTSGLFTCLFGLGYIYDIHSLGFYIFV--QVANGLVQTTGWPSVVTC 172

  Fly   154 LSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCV----GIVWSFVWL 214
            :..|.....||.::|...|.:..|.::...::||..||:  |..:|.:||.:    |::..|..:
Zfish   173 IGNWFGKGRRGLIMGLWNSHTSVGNILGSLIAGYYVSSN--WGLSFIVPGVIIAAMGVICFFFLI 235

  Fly   215 YLCSSTPAQHP---------TITPNERRFIESSGQARRPSDAGREEQPRPPTPWW---------- 260
                    :||         :..|:.::|.:|........|...:.:|......|
Zfish   236 --------EHPNDLKTASTQSSAPSSQKFHKSCNGVNGHKDLYLQYKPGAKAQSWDTELLLGQES 292

  Fly   261 ----------------------------RIFTSVPF-LVLVLAHCANNWGFWTLLTEIPTFMKNV 296
                                        ||...|.| |.|:.|...:    :|.|..:|.::...
Zfish   293 IGVCVPVQQVVVVKSEAEPSAISFMGALRIPGVVEFSLCLLFAKLVS----YTFLFWLPLYITKA 353

  Fly   297 LGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGTVIPL----------GFSRKFFNTLGMW 351
            ..:|.|..|.||.|.....|:...:...:||.:.:|.|...:          |||......||..
Zfish   354 AHLDAKKAGDLSTLFDVGGIVGGILAGVISDKMHKRATTCAVMLLLAAPMLYGFSMMSQFGLGPT 418

  Fly   352 LPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANF 416
            :.||.:.|      |..|...|  |:|.||:.:..|:.....|...||     |:..|.:...:.
Zfish   419 IGMLLVCG------GLVNGPYA--LITTAVSADLGTHKSLKGNARALS-----TVTAIIDGTGSV 470

  Fly   417 MSILAPLIVGLIV---WDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRP 471
            .:.:.||:.||:.   ||:        ||:......|...||.:......::...:||
Zfish   471 GAAVGPLLAGLLSARGWDQ--------VFYMLMTADFFALLLLLRLVMKELRYHRNRP 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	111/509 (22%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	111/499 (22%)
slc37a1	NP_001007440.1	UhpC	92..501	CDD:332119	95/445 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840