DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and CG7091

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	117/495 - (23%)
Similarity:	204/495 - (41%)	Gaps:	60/495 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VRHLQCILVFFGLAVAYSLRVNLSVAIVAM------------------TDRNAS----------- 61
            ||....|..|....:..::|..|.:.|:.|                  |:.|.:
  Fly    26 VRLTYAICAFLATCLHAAMRNMLGMIILKMVMPRPEDALVVPAGLSRLTEGNVTSTGRCGSPRVV 90

  Fly    62 -NPDFPE-----FDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLT 120
             ||...|     ..|..:.:......:::||||:....|||:....:|.:....::..:...:|.
  Fly    91 FNPQIQETQSGDLPWTRNQELTFPGVYYYGYVVSISLSGYLADRCSSKRLFIVSLIFEAVAYILL 155

  Fly   121 PFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVS 185
            |..| :..:...||...:.||..|...|:.:.....||...||..|:.:.|||...|::::..|:
  Fly   156 PAMA-HSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTERTALLSFAYSGLLMGSMLVYPVA 219

  Fly   186 GYIASSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGRE 250
            .|:  |:.||..:||:.|.||:.:.....:|...|..|||.|:..|..::...     .|..|::
  Fly   220 SYL--SNFGWELSFYVVGGVGLSFGIACCFLVYDTVEQHPRISNEEVDYLRQG-----KSQLGQQ 277

  Fly   251 EQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAM 315
            .||....||..:..:.|....:|.|..:.:.|..::..:|.||:..:..|::..|.|||.||...
  Fly   278 RQPVVTIPWKSLLAAPPVYAFILTHMFHTYTFLVIVQLMPRFMREAMEFDLREVGFLSAAPYLGG 342

  Fly   316 IL--LTCVFIWLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLT 378
            |.  :.|:   |..:..:|.........|:....:...| ..:|||:..:...:..: |.:.:..
  Fly   343 ICSKVMCI---LGGSYVERRVGPDQNCVRRMLYGICSIL-TTSLIGVIILANCDDKI-LVLVMFA 402

  Fly   379 AAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVW----DETNPAQWR 439
            ..:||....:.|:....:..:|::||.|.|:.|..|:....|||.:|..:|.    ||.|.....
  Fly   403 FMMATTDMGFSGYWPTLLYFAPSFAGLLSGLANGMAHLSGFLAPHLVAALVHTGSKDEWNVVLMT 467

  Fly   440 IVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRP-TTRTPSP 478
            ::.|.|     :..|:|.....|.:|||:.|. ..:|.||
  Fly   468 LIVFNT-----MAMLVFAFCSSTNLQPWDPRSRMEKTASP 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	113/483 (23%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	107/468 (23%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	105/438 (24%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	95/384 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970