DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS15 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001009713.1	Gene:	Slc17a5 / 363103	RGDID:	1311388	Length:	495	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	173/485 - (35%)
Similarity:	258/485 - (53%)	Gaps:	59/485 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CCNHNGYQQIGNTGPRFGVRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNAS----------- 61
            ||:               .|:...:|.|.|..|.|:||||||||:|.|.|.|::
  Rat    35 CCS---------------ARYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLTDNRTSKECA 84

  Fly    62 ----------NPDFPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCL 116
                      |....::.|:..|:.::|.|||:||:||||||||:::..|.|.:|..|:|..:..
  Rat    85 EHSAPVKVHHNHTGKKYQWDAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLGLGILGTAVF 149

  Fly   117 ALLTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVM 181
            .|.||. |.:.|...::||||::||.:||.||:.|...|.|||..||.:|:..:|:|:|.|||:.
  Rat   150 TLFTPL-AADLGVVALIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVIS 213

  Fly   182 LSVSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSD 246
            |.:||.|. ..:.|...||:.|.|||||..:|:::.|.||..|.||:..|:.:|.||.:.:..|
  Rat   214 LPLSGIIC-YYMNWTYVFYLFGLVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSS- 276

  Fly   247 AGREEQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALP 311
                   :...||..|..|:|...:|:||.:.||.|:||||.:||:||.:|..:::.||.|||||
  Rat   277 -------QKVVPWVSILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSALP 334

  Fly   312 YFAMILLTCVFIWLSDTLKQRGTVIPLGFS----RKFFNTLGMWLPMLALIGLGYITEGEANVRL 372
            ||...|...|....:|.|:     :...||    |:.|:.:||..|.:.|:..|:|   ..:..|
  Rat   335 YFGCWLCMIVCGQAADYLR-----VKWNFSTISVRRIFSLIGMVGPAVFLVAAGFI---GCDYSL 391

  Fly   373 AIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQ 437
            |:..||.:.........||.:||:|::|:|||.|:||||..|....::.|:|...:..|.| ..:
  Rat   392 AVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLGITNTFATIPGMIGPIIAKSLTPDNT-IKE 455

  Fly   438 WRIVFFFTAFVYFIGNLLFMLFGRTRVQPW 467
            |:.||...|.:...|.:.|.||.:..||.|
  Rat   456 WQTVFCIAAAINVFGAIFFTLFAKGEVQNW 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	171/475 (36%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	165/452 (37%)
Slc17a5	NP_001009713.1	2A0114euk	30..491	CDD:129972	173/485 (36%)
Slc17a5	NP_001009713.1	MFS	99..478	CDD:119392	148/397 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850