DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and MFS18

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	114/462 - (24%)
Similarity:	184/462 - (39%)	Gaps:	92/462 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ILVFFGLAVAYSLRVNLSVAIVAMTDRNASNPDFPEFDWNESTKSYLLSSFFWGYVVTQIPGGYL 96
            |.:..|..:.||.|..:.:.:.|:....         .|:::....:||||||||.:||:.|||.
  Fly    31 ITLITGTCMLYSTRTTMPLLVPAVASAQ---------KWSKTDSGTVLSSFFWGYTLTQVVGGYF 86

  Fly    97 SAIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTV----------VVVLRAVQGLCQGVIFPSTH 151
            |..:|.:.::.:..:..|.:..|.|...    ||.          :|.:|.:.|..|||.|||..
  Fly    87 SDRFGGQRVILFAAIGWSLITFLMPTII----WTAGSIKSYAIPFIVAIRILNGALQGVHFPSMI 147

  Fly   152 TFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYL 216
            :..|:.....||....|...:||..|| ::..:.|.......||...|.:.|.:||.|:.|
  Fly   148 SLTSQNLCPNERSSFFGLLTAGSALGT-LLTGIMGSFLLDYFGWSYVFRVIGLMGIAWALV---- 207

  Fly   217 CSSTPAQHPTITPNERRFIESSGQARR------PSDAGREEQPRPPT--PWWRIFTSVPFLVLVL 273
                           .|:...:|:..|      ||.....:.|...:  ||.|.|..:.|...||
  Fly   208 ---------------LRYYAMAGERNRIINIATPSRLCANKSPAETSAVPWLRYFRRLSFWACVL 257

  Fly   274 AHCANNWGFWTLLTEIPTFMKNVLGMD-----IKNNGPLSALP---YFAMILLTCVFI--WLSDT 328
            .|......|:.||:.:||:..:  |..     :.|..|..|||   .||..|.|.:..  |.:.|
  Fly   258 THACEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWLALPPCTLFAKYLTTRLLAREWHTTT 320

  Fly   329 LKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLGFH- 392
            :            ||...:.......|||    ::....::...|:..:|..:...     |||
  Fly   321 V------------RKVIQSCCFAAQNLAL----FVMSRTSDFHTALICMTIIIGGT-----GFHN 364

  Fly   393 ----VNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGN 453
                ||..||:|.::|::.|:.|........|...:.|.|: :.|.  .|.:||...|.:..:|.
  Fly   365 NAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHIL-ELTQ--SWPMVFSAAAGINLVGW 426

  Fly   454 LLFMLFG 460
            ::|::||
  Fly   427 IIFIVFG 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	114/462 (25%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	112/459 (24%)
MFS18	NP_608835.1	MFS	30..432	CDD:119392	112/459 (24%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	101/420 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451996
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.890