DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	480	Identity:	101/480 - (21%)
Similarity:	173/480 - (36%)	Gaps:	120/480 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RVNLSVA-------IVAMTDR----NASNPDFPE-FDWNESTKSYLLSSFFWGYVVTQIPGGYLS 97
            |::|.:|       :||..||    ||.....|| ........:.:.|.|:..:::.::|...|.
pombe    54 RLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLM 118

  Fly    98 AIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEE 162
            .....|.||.:.|:..|...:.|.||...||   ::..|.|.|.|:..:||....:|:......|
pombe   119 KKVQPKRMLAFIVISYSLTTIFTGFCHNFGG---LLAARLVLGFCEAGLFPCLALYLTMIYSRVE 180

  Fly   163 RGRLVGYTYSGS----------QFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYLC 217
            ....:.|.::.|          .:..:.|..|.|:     .||...|.|.|.:|.|.. |.:|.
pombe   181 LAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGF-----AGWRWLFIIEGLIGFVCG-VAVYF- 238

  Fly   218 SSTPAQHPTITPNE----------RRFIESSGQARRPSD--AGREEQPRPPTPWWR----IFTSV 266
                     |.||:          .:.:....|..|.:|  |...:        |:    .||..
pombe   239 ---------IIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAHFD--------WKGVKSAFTDF 286

  Fly   267 PFLVLVLAHCANN---WGFWTLLTEIPTFMKNVLGMDIKNNGPLS----ALPYFAMILLTCVFI- 323
            ...:..|:....:   :||.|.|..|      :.||...:   ||    .:|.:  ||....:|
pombe   287 KVYLYALSEFGQDTCLYGFSTFLPAI------ISGMGYTS---LSVQYMTIPVY--ILGAATYIA 340

  Fly   324 --WLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSA 386
              :|||....||.::          .:|...|::..|.|......::.:..|..|.:..|.|.:
pombe   341 ASFLSDRFHHRGIIL----------IIGNIFPIVGYILLLACQNNKSVLYFACYLCSVGVYTGA- 394

  Fly   387 TYLGFHVNHI--DLSPNY-AGTLMGITNCAANFMSILA--------PLIVGLIVWDETNPAQWRI 440
               |.:|..:  :::|:| ..|.:.:....||...|||        ..|.|.:.         .:
pombe   395 ---GLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRYPPKYIAGHLT---------SL 447

  Fly   441 VFFFTAFVYFIGNLLFMLFGRTRVQ 465
            :..|.:.|..:.|:.|:....::.|
pombe   448 IAIFISTVLHVVNIFFLKHQNSKKQ 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	101/480 (21%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	100/472 (21%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	94/452 (21%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	91/421 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050