DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and Slc37a1

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001229356.1	Gene:	Slc37a1 / 224674	MGIID:	2446181	Length:	531	Species:	Mus musculus

Alignment Length:	476	Identity:	113/476 - (23%)
Similarity:	182/476 - (38%)	Gaps:	124/476 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 NASNPDFPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYG----AKYMLFYGVLICSCLALL 119
            |.::..:..||.|...:  ||.:..:.::.....|.|||.|.|    .:|.|.:|:|
Mouse    81 NETDCGWAPFDKNNYQQ--LLGALDYAFLCAYAIGMYLSGIIGERLPIRYYLTFGML-------- 135

  Fly   120 TPFCAVNGGWTVV---------------VVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGY 169
                 .:|.:|.:               ||.:.:.||.|...:||..|.||.|.....||.::|.
Mouse   136 -----ASGAFTALFGLGYFYNIHSLGFYVVTQIINGLVQTTGWPSVVTCLSNWFGKGRRGLIMGI 195

  Fly   170 TYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCV----GIVWSFVWLYL--------CSSTPA 222
            ..|.:..|.::...::||..|:.  |..:|.:||.:    |||   .:|:|        ||||..
Mouse   196 WNSHTSVGNILGSLIAGYWVSTC--WGLSFIVPGAIVAAMGIV---CFLFLIEHPKDVKCSSTLP 255

  Fly   223 QHPTITPN---------ERRFIESSG------QARRPSDAGREEQPRPP---------------- 256
            .||..:.|         :..:.|.:|      |....||.   :.|..|
Mouse   256 THPRASENGINRFRLQKQTTYSEKNGPLDPELQCLLLSDG---KNPLHPSHIVVLPADGNMAAIS 317

  Fly   257 -TPWWRIFTSVPF-LVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSAL----PYFAM 315
             |...||...:.| |.|:.|...:    :|.|..:|.::.:|..:|.|..|.||.|    ..|..
Mouse   318 FTGALRIPGVIEFSLCLLFAKLVS----YTFLFWLPLYITSVDHLDAKKAGELSTLFDVGGIFGG 378

  Fly   316 ILLTCVFIWLSDTLKQRGT--------VIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRL 372
            ||...:    ||.|::|.:        ..|..:.....:.:|:...:..|:..|.:..|
Mouse   379 ILAGVI----SDRLEKRASTCGLMLLLAAPTLYVFSSVSRMGLEATIAMLLLSGALVSG------ 433

  Fly   373 AIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQ 437
            ...|:|.||:.:..|:.....|...||     |:..|.:...:..:.|.||:.|||     :|:.
Mouse   434 PYALITTAVSADLGTHKSLKGNSHALS-----TVTAIIDGTGSVGAALGPLLAGLI-----SPSG 488

  Fly   438 WRIVFFFTAFVYFIGNLLFML 458
            |..||:...|..... |||::
Mouse   489 WSNVFYMLMFADACA-LLFLV 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	113/476 (24%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	113/476 (24%)
Slc37a1	NP_001229356.1	MFS_SLC37A1_2	21..514	CDD:340902	113/476 (24%)
Slc37a1	NP_001229356.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..72
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840