Protein Alignment MFS15 and SLC37A2

DIOPT Version :9

• Sequence 1: NP_611375.2
• Gene: MFS15 / 37168
• FlyBaseID: FBgn0034392
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 107/467 - (22%)
• Similarity: 175/467 - (37%)
• Gaps: 71/467 - (15%)

  Fly    44 LRVNLSVAIVAMTDRNASNPDFPEFDW---NESTKSYLLSSFFWGYVVTQIPGGYLSAIYG---- 101
            |..|.|..|..:.|.::.| |.....|   ::.....||......:::....|.::|.::|
Human    50 LHQNCSEQIKPINDTHSLN-DTMWCSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLP 113

  Fly   102 AKYMLFYGVLICSCLALLTPFCAVNGGWTV-----VVVLRAVQGLCQGVIFPSTHTFLSKWAPAE 161
            .:|.|..|:|:.   .|.|....:...|.:     .||::...||.|...:||..|.:..|....
Human   114 LRYYLSAGMLLS---GLFTSLFGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKG 175

  Fly   162 ERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWSFV-WLYL--------C 217
            :||.::|...|.:..|.::...::|...:..  |..:|.:||.:..|...: :|:|        |
Human   176 KRGFIMGIWNSHTSVGNILGSLIAGIWVNGQ--WGLSFIVPGIITAVMGVITFLFLIEHPEDVDC 238

  Fly   218 SSTPAQH----------PTITPNERRFIESSG-QARRPSDAGREEQPRPPTPW--WRIFTSVPF- 268
            :  |.||          |....|....|..|| :.......|..|:|...:.:  .||...|.|
Human   239 A--PPQHHGEPAENQDNPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFS 301

  Fly   269 LVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRG 333
            |.|:.|...:    :|.|..:|.::.||.....|..|.||.|.....|:...|...:||....|.
Human   302 LCLLFAKLVS----YTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRA 362

  Fly   334 T--------VIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLG 390
            |        ..|:.|...:....|:...::.||..|.:..|      ...|:|.||:.:..|:..
Human   363 TTCCVMLILAAPMMFLYNYIGQDGIASSIVMLIICGGLVNG------PYALITTAVSADLGTHKS 421

  Fly   391 FHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLL 455
            ...|...||     |:..|.:...:..:.|.||:.|||     :|..|..||:.......:..||
Human   422 LKGNAKALS-----TVTAIIDGTGSIGAALGPLLAGLI-----SPTGWNNVFYMLISADVLACLL 476

  Fly   456 FMLFGRTRVQPW 467
            ........:..|
Human   477 LCRLVYKEILAW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	107/467 (23%)
		MFS	31..459	CDD:119392	106/457 (23%)
SLC37A2	NP_938018.1	UhpC	25..478	CDD:332119	106/455 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S3312
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860