DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	479	Identity:	144/479 - (30%)
Similarity:	237/479 - (49%)	Gaps:	45/479 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VRHLQCILVFFGLAVAYSLRVNLSVAIVAMTD-------RNASN---------------PDFPE- 67
            :|:...:::.|......:.||:||:||:||.:       .|||.               .||..
Mouse    16 LRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVMDLLSNQSRGIKDFSTR 80

  Fly    68 ---FDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGGW 129
               :.|:..|:..:.||..:|.::|.||.|||:.|:|||.:|..|:||.|.|.|.||. |.:.|.
Mouse    81 AAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPL-AADFGV 144

  Fly   130 TVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVML--SVSGYIASSS 192
            .:|:|:|.|||:.||:.:....|..:||||..||.:|.....||...|:|.:|  .:.|.|..:.
Mouse   145 ILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLHHPLCGRINLTG 209

  Fly   193 LGWPSTFYIPG-CVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGREEQPRPP 256
            .|  ..||:.. |:|.|...:|..:....|..||.|:..|:..|.|       |.|.:...||..
Mouse   210 TG--LAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITS-------SVAQQSSSPRRS 265

  Fly   257 TPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCV 321
            .|...:...:|...:.:...::.|....::|.:||::..||.::|:::|.||:||:.|....|.:
Mouse   266 VPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTIL 330

  Fly   322 FIWLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSA 386
            ...::|.|..| .::.|...||.|::||:.||.|..:.|.::|   ::....|.||.....|::.
Mouse   331 GGQMADFLLSR-NLLSLITVRKLFSSLGLLLPSLCAVALPFVT---SSYIATIVLLILIPGTSNL 391

  Fly   387 TYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFI 451
            ...||.:|.:|::|.||..||||:........|::....|.:: .:.:.:.||.|||.:|.|...
Mouse   392 CDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLI-SQDSESGWRNVFFLSAAVNMF 455

  Fly   452 GNLLFMLFGRTRVQPW-NSRPTTR 474
            |.:.:::||:..:|.| ..|..||
Mouse   456 GLIFYLIFGQAEIQSWAKERTLTR 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	141/472 (30%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	136/456 (30%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	136/457 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750