DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and T22F3.8

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_504013.1	Gene:	T22F3.8 / 178781	WormBaseID:	WBGene00020698	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	113/511 - (22%)
Similarity:	191/511 - (37%)	Gaps:	102/511 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LQCIL-VFFGLAVAYSLRVNLSVAIVAMTDRN-----------------ASN------------P 63
            |.|:. .||.|.||:.|.   |..:..|...|                 .||            .
Worm     9 LHCLYRTFFNLKVAFFLG---SAGLTMMLLNNYYRFIVLLVGFLCLASLCSNYLIINFTFICMKH 70

  Fly    64 DFPE------------FDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCL 116
            ||.:            :|:....|.::|.:...|.::..:|...|...|||::..|...:: ||:
Worm    71 DFSDGFTEINGTRQSIYDYTPDDKKWILWAVAAGTIIGTVPMNLLLVKYGARFPFFLSGIV-SCI 134

  Fly   117 AL-LTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVV 180
            :. |.|| |....:..:::||.:||......|.:......:|||..|....|......:...:::
Worm   135 STSLIPF-AAKWNFAFLIILRFIQGFSFSADFAAIGLLAVRWAPLAETAIFVAVLTCFNAIASMI 198

  Fly   181 MLSVSGYIASSSLGWPSTFYIPGCVG----IVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQA 241
            ....:|.|..|||||..::|:...||    ::|.||::        .||..|   ||......|:
Worm   199 TNMATGLICVSSLGWKWSYYLHSIVGAILFVLWYFVYI--------DHPQDT---RRVSGKELQS 252

  Fly   242 RRPSDAGREEQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLL------TEIPTFMKNVLGMD 300
            .:.:.:......:...|:.::.|| |.::.|.|:     .|:.|.      |.||.::..||...
Worm   253 IQKNKSEAHLSKKCDVPYIKLATS-PVILCVWAN-----AFFDLTAAIMFSTYIPLYLHEVLKFG 311

  Fly   301 IKNNGPLSALPYFAMILLTCVFIWLSDTLK--------QRGTVIPLGFSRKFFNTLGMWLPMLAL 357
            :...|..|:|.:...:.:...|..:||.::        |....|.:|.|..||.::|: :||
Worm   312 VTETGFYSSLIHGICLPVRLCFGIISDKIQFISEPVKIQIFNTISVGGSGLFFASIGL-IPM--- 372

  Fly   358 IGLGYITEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAP 422
                   |.......:..:..:.:..|...:....|.|.....:...|.:....|.|.|   :||
Worm   373 -------EYRGWSVFSCIMTMSCIGVNPGGFYKVAVLHSRQFAHVVLTAIQWIKCLALF---VAP 427

  Fly   423 LIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRPTTRTPSP 478
            .:|.:.|.:|:...||..||........|.|:|...|...:...|     |.|..|
Worm   428 ALVSIFVTNESIRQQWIWVFLIVGGGMVITNILGFFFLTDKPAEW-----TDTDEP 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	110/500 (22%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	107/488 (22%)
T22F3.8	NP_504013.1	MFS	87..464	CDD:391944	93/409 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820