DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	151/466 - (32%)
Similarity:	227/466 - (48%)	Gaps:	32/466 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RFGVRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDR-------NAS------NPDFPEFDWNEST 74
            |:|:    .||:.|...|..:.||.|::.:|||.::       |.|      |...|...|:...
  Rat    17 RYGL----AILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDI 77

  Fly    75 KSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTVVVVLRAVQ 139
            :..:|||.|.|.||.|:|.||||..|..|.::...:.:.|.|:||.| .|...|..:|:|.|.:|
  Rat    78 QGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIP-PAAQVGAALVIVCRVLQ 141

  Fly   140 GLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGC 204
            |:.||.:....|....||||..|||||...|.||...|..:.|.|||:|. ..||||..|||.|.
  Rat   142 GIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFIC-DLLGWPMVFYIFGI 205

  Fly   205 VGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGREEQPRPPTPWWRIFTSVPFL 269
            ||.|.|..|..|....|..||.::.:|:.:|.||  ..:...:||:..|..     .:..|:|..
  Rat   206 VGCVLSLFWFILFFDDPNNHPYMSSSEKDYITSS--LMQQVHSGRQSLPIK-----AMLKSLPLW 263

  Fly   270 VLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGT 334
            .::|...|..|....|:|..|||:...|.::::.||.||:|||....:...|...:||.|..| .
  Rat   264 AIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSR-K 327

  Fly   335 VIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLS 399
            :..:...||.|.|||::.|::.::.|.|::   .|....:..||.|.:|.|.::.|..:|.:|::
  Rat   328 IFSVVAVRKLFTTLGIFCPVIFVVCLLYLS---YNFYSTVIFLTLANSTLSFSFCGQLINALDIA 389

  Fly   400 PNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRV 464
            |.|.|.|..:|.....|..:::..:.|||:..:...| |...||..|.:.......::||.:..:
  Rat   390 PRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEYA-WHKNFFLMAGINVTCLAFYLLFAKGDI 453

  Fly   465 QPW-NSRPTTR 474
            |.| ....|||
  Rat   454 QDWAKETKTTR 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	148/459 (32%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	142/440 (32%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	149/464 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910