Protein Alignment MFS15 and SLC17A3

DIOPT Version :9

• Sequence 1: NP_611375.2
• Gene: MFS15 / 37168
• FlyBaseID: FBgn0034392
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 136/488 - (27%)
• Similarity: 222/488 - (45%)
• Gaps: 64/488 - (13%)

  Fly    23 RFGVRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNASNPD----------------------- 64
            |:|:    .:::.|......:..|.:::.:|||.  |:::|.
Human    38 RYGI----ALVLHFCNFTTIAQNVIMNITMVAMV--NSTSPQSQLNDSSEVLPVDSFGGLSKAPK 96

  Fly    65 -----FPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCA 124
                 .|.:||:...:..:..:..:|.::|..|.|||:...|.|.::...:...|.|.|..|. |
Human    97 SLPAKAPVYDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIPL-A 160

  Fly   125 VNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIA 189
            .:.|..:::|.|.||||.|..|.........||.|.:||.||.....||...|....:.:.|:|
Human   161 TDFGIVLLIVTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAILIGGFI- 224

  Fly   190 SSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGREEQPR 254
            |.:||||..|||.|.||.|...:|..:....|..:|.|:.:|:.:|.||    .....|..:||.
Human   225 SETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISS----LKQQVGSSKQPL 285

  Fly   255 PPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLT 319
            |.....|   |:|...:.|...::.|...|::..|||::.:|..::|::||.|||||:....::.
Human   286 PIKAMLR---SLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIVAWVIG 347

  Fly   320 CVFIWLSD-TLKQRGTVIPLGFSRKFFNTLGMWLPMLALI------GLGYITEGEANVRLAIGLL 377
            .|..:|:| .|.::..:|.:   ||....||. ||..|||      ..||||        |..||
Human   348 MVGGYLADFLLTKKFRLITV---RKIATILGS-LPSSALIVSLPYLNSGYIT--------ATALL 400

  Fly   378 TAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVF 442
            |.:...::....|.::|.:|::|.|:..|||.:...::...::.|.:.|.:: .:.....||.||
Human   401 TLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLL-SQDPEFGWRNVF 464

  Fly   443 FFTAFVYFIGNLLFMLFGRTRVQPW-NSRPTTR 474
            |....|..:|.|.:::||...||.| ..|..||
Human   465 FLLFAVNLLGLLFYLIFGEADVQEWAKERKLTR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	133/481 (28%)
		MFS	31..459	CDD:119392	126/462 (27%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	134/486 (28%)
		MFS	98..481	CDD:119392	119/404 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750