Protein Alignment MFS15 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_611375.2
• Gene: MFS15 / 37168
• FlyBaseID: FBgn0034392
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 142/493 - (28%)
• Similarity: 240/493 - (48%)
• Gaps: 55/493 - (11%)

  Fly     9 CNHNGYQQIGNTGPRFGVRH-LQCILVFFGLAVAYSLRVNLSVAIVAMTDRNA--SNPD------ 64
            |:..|:         ..||| |..||.....:: |:.::|||:||.||.:..|  |.|:
Human    27 CSRKGF---------CSVRHGLALILQLCNFSI-YTQQMNLSIAIPAMVNNTAPPSQPNASTERP 81

  Fly    65 ------------------FPEFDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVL 111
                              .|.:||:...:..:|||..:|..:..||.||::.|:||||::..|:.
Human    82 STDSQGYWNETLKEFKAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLF 146

  Fly   112 ICSCLALLTPFCAVNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQF 176
            |.|.|.|..|. |.|.|..:::|||.|||:.|.::....::...||||..||.:|.....|||..
Human   147 ISSFLTLFIPL-AANAGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSML 210

  Fly   177 GTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQA 241
            |:.::| ::|.:...::|||..|||.|.:|.....:|..|....|..||.|:..|:|:|..
Human   211 GSFIVL-LAGGLLCQTIGWPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVC---- 270

  Fly   242 RRPSDAGREEQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGP 306
               |.|.::..|....|...:..|:|...:::::....|.|:|::...||::.:||..:::::|.
Human   271 ---SLAQQDCSPGWSLPIRAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGI 332

  Fly   307 LSALPYFAMILLTCVFI--WLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEAN 369
            |||||:  ::...|:.:  .|:|.|..| .::.|...||.|..:|:..|.:.|:.|.::....:
Human   333 LSALPF--VVGCICIILGGLLADFLLSR-KILRLITIRKLFTAIGVLFPSVILVSLPWVRSSHS- 393

  Fly   370 VRLAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETN 434
              :.:..|..:.|.:|....|..||.:|::|.|.|.|.|:....|:....::|...|..: .:.:
Human   394 --MTMTFLVLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFI-SQDS 455

  Fly   435 PAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRPT 472
            ...||.||..:|.|...|.:.:::|||..||.|....|
Human   456 EFGWRNVFLLSAAVNISGLVFYLIFGRADVQDWAKEQT 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	MFS_SLC17	31..460	CDD:340876	129/456 (28%)
		PTZ00334	228..>281	CDD:240366	9/52 (17%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	129/457 (28%)