DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS15 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	480	Identity:	158/480 - (32%)
Similarity:	250/480 - (52%)	Gaps:	27/480 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FGV--RHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNASNPD------FPEFDWNESTKSYLLS 80
            ||:  |::..||...|..:::.:|.||.||:|:|.:.:....|      ..:|.|:..|...:..
Zfish    57 FGLPRRYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYRDGKPYIVKAQFSWDPETVGMIHG 121

  Fly    81 SFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTVVVVLRAVQGLCQGV 145
            ||||||:|||||||::...:.|..:..:.|:..|.|.::.| .|....:..|:::|.:|||.:||
Zfish   122 SFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIP-TAARMHFGCVILVRILQGLVEGV 185

  Fly   146 IFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSLGWPSTFYIPGCVGIVWS 210
            .:|:.|...:||||..||.||....:.||..|.|:.:.::|.:...| ||.|.||:.|..|:.|.
Zfish   186 SYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLVQYS-GWSSVFYVYGSFGVCWY 249

  Fly   211 FVWLYLCSSTPAQHPTITPNERRFIESS-GQARRPSDAGR-EEQPRPPTPWWRIFTSVPFLVLVL 273
            ..|:.:...:||.||||||.||::||.: |::     ||. ....:..|||.:.|||:|...:::
Zfish   250 LFWILVSYESPAAHPTITPEERKYIEDAIGES-----AGLVNPLTKFNTPWRQFFTSMPVYAIIV 309

  Fly   274 AHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFIWLSDTLKQRGTVIPL 338
            |:...:|.|:.||...|.:.:.|...:|...|.|||||:..|.::..:...|:|.|:....:...
Zfish   310 ANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLADYLRTHNLMTTT 374

  Fly   339 GFSRKFFNTLGMWLPMLALIGLGYI-TEGEANVRLAIGLLTAAVATNSATYLGFHVNHIDLSPNY 402
            .. ||..|..|..|....|:.:|:. |:|     :||..|..||..:.....||:|||:|::|.|
Zfish   375 NV-RKLMNCGGFGLEATFLLVVGFSHTKG-----VAISFLVLAVGFSGFAISGFNVNHLDIAPRY 433

  Fly   403 AGTLMGITNCAANFMSILAPLIVGLIVWDETNPAQWRIVFFFTAFVYFIGNLLFMLFGRTRVQPW 467
            |..||||:|.......::.|||||.:..::|. .:|:.||...:.|::.|.:.:.||.....|||
Zfish   434 ASILMGISNGVGTLSGMVCPLIVGAMTKNKTR-EEWQYVFLIASLVHYGGVIFYGLFASGEKQPW 497

  Fly   468 NSRPTTRTPSPG--GGGERDEGTED 490
            .....|.....|  |..|..:.||:
Zfish   498 AEPENTSEEKCGILGEDELADETEE 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	152/455 (33%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	144/436 (33%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582489
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.760