DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15093 and hibadha

DIOPT Version :9

Sequence 1:	NP_001188972.1	Gene:	CG15093 / 37166	FlyBaseID:	FBgn0034390	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001003646.1	Gene:	hibadha / 445252	ZFINID:	ZDB-GENE-040801-264	Length:	328	Species:	Danio rerio

Alignment Length:	292	Identity:	141/292 - (48%)
Similarity:	191/292 - (65%)	Gaps:	2/292 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYAKTSELAKNSDFVITMLPNN 95
            :||:||||||..||.||:|.|:.:...|....:|..|...||.:....:|:|:.:|.:|||||::
Zfish    35 VGFIGLGNMGTPMARNLLKNGYPVIATDAFPESCKELQDSGAQILDSPAEVAEKADRIITMLPSS 99

  Fly    96 AIVDASY--DEMTADGVNKDTIFIDSSTISPDLVKSLQKKISAKGARFIDAPVSGGVPGAEQATL 158
            ..|...|  .......|.|.|:.||||||.|.:.|.:.......||.|:||||||||..|..|.|
Zfish   100 PNVIEVYTGSNSILRKVKKGTLLIDSSTIDPAVSKEMAVAAEKMGAVFMDAPVSGGVGAASLAKL 164

  Fly   159 TFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMMLAISMIGVSEAMNLAVRQGLD 223
            ||:|||.|.||||.:.:|.|||..:.:||..|.|||||:||||:|||.|:|.:|.|||.:|.|||
Zfish   165 TFLVGGVEEEYNAAQELLTCMGANVVYCGQVGSGQAAKICNNMLLAIGMLGTAETMNLGIRLGLD 229

  Fly   224 ANVFAEIINSSTGRCWASEIYNPVPGVCPSAPANRDYAGGFSSALITKDLGLASGVANASNSPIP 288
            ..:.|:|:|.|:||||:|:.|||||||....|:..:|.|||.:.|:.||||.|...|.::.:|||
Zfish   230 PKLLAKILNMSSGRCWSSDTYNPVPGVMEGVPSANNYQGGFITTLMAKDLGFAQNTATSTRTPIP 294

  Fly   289 LGSLAHKVYQSLCDKGLGNKDFSVVYDLMKKE 320
            ||||||:||:::|.:|..|||||.|:..:::|
Zfish   295 LGSLAHQVYRTMCARGYSNKDFSSVFQFLREE 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15093	NP_001188972.1	NAD_binding_2	29..187	CDD:281445	68/157 (43%)
		HIBADH	33..318	CDD:130753	139/286 (49%)
		NAD_binding_11	190..314	CDD:291499	69/123 (56%)
hibadha	NP_001003646.1	NAD_binding_2	32..193	CDD:281445	68/157 (43%)
		HIBADH	37..324	CDD:130753	139/286 (49%)
		NAD_binding_11	196..323	CDD:291499	70/126 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4049
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15088
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2825
OMA	1	1.010	-	-		QHG54899
OrthoDB	1	1.010	-	-		D524012at33208
OrthoFinder	1	1.000	-	-		FOG0003551
OrthoInspector	1	1.000	-	-		otm25131
orthoMCL	1	0.900	-	-		OOG6_101839
Panther	1	1.100	-	-	O	PTHR22981
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1549
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.980