DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15093 and hibadhb

DIOPT Version :9

Sequence 1:	NP_001188972.1	Gene:	CG15093 / 37166	FlyBaseID:	FBgn0034390	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_957454.1	Gene:	hibadhb / 394135	ZFINID:	ZDB-GENE-040426-1582	Length:	329	Species:	Danio rerio

Alignment Length:	311	Identity:	143/311 - (45%)
Similarity:	198/311 - (63%)	Gaps:	11/311 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QTLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYAKTSE 80
            |..:|:|:::   ..:||:||||||..||.||||.|:.:...|:...:|..|...||.:....::
Zfish    23 QVSIRSMASK---TQVGFIGLGNMGNPMAKNLIKHGYPVIATDVFPESCKELQELGAQILDSPAD 84

  Fly    81 LAKNSDFVITMLPNNAIVDASYDEMTADG-----VNKDTIFIDSSTISPDLVKSLQKKISAKGAR 140
            :|..:|.:|||||:|..|   .|..|...     |.|.::.||||||.|.:.|.:.......||.
Zfish    85 VADKADRIITMLPSNPNV---VDVYTGPNGILKKVKKGSLLIDSSTIDPAVSKEMAVAAEKLGAV 146

  Fly   141 FIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMMLAI 205
            |:.|||||||..|....|||||||.|.|:||.|.:|.|||..:.:||..|.|||||:||||:|||
Zfish   147 FMGAPVSGGVGAATSGKLTFMVGGPEEEFNAAKELLSCMGANVVYCGQVGTGQAAKICNNMLLAI 211

  Fly   206 SMIGVSEAMNLAVRQGLDANVFAEIINSSTGRCWASEIYNPVPGVCPSAPANRDYAGGFSSALIT 270
            .|||.:|.|||.:|.|||..:.|:|:|.|:||||:|:.|||||||....|:..:|.|||.:.|:|
Zfish   212 GMIGTAETMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMEGVPSANNYQGGFGTTLMT 276

  Fly   271 KDLGLASGVANASNSPIPLGSLAHKVYQSLCDKGLGNKDFSVVYDLMKKEK 321
            ||||||...|..:.:|:.|||:||::|:.:|.:|..|||||.|:..:::|:
Zfish   277 KDLGLAQNSATNTKTPVLLGSVAHQIYRMMCGRGYANKDFSSVFQFLREEE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15093	NP_001188972.1	NAD_binding_2	29..187	CDD:281445	68/162 (42%)
		HIBADH	33..318	CDD:130753	138/289 (48%)
		NAD_binding_11	190..314	CDD:291499	68/123 (55%)
hibadhb	NP_957454.1	NAD_binding_2	32..193	CDD:281445	68/166 (41%)
		HIBADH	37..324	CDD:130753	138/289 (48%)
		NAD_binding_11	196..323	CDD:291499	69/126 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4049
eggNOG	1	0.900	-	-		E1_COG2084
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15088
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2825
OMA	1	1.010	-	-		QHG54899
OrthoDB	1	1.010	-	-		D524012at33208
OrthoFinder	1	1.000	-	-		FOG0003551
OrthoInspector	1	1.000	-	-		otm25131
orthoMCL	1	0.900	-	-		OOG6_101839
Panther	1	1.100	-	-	LDO	PTHR22981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2375
SonicParanoid	1	1.000	-	-		X1549
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870