Protein Alignment Mctp and TCB2

DIOPT Version :9

• Sequence 1: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_014312.1
• Gene: TCB2 / 855637
• SGDID: S000005031
• Length: 1178
• Species: Saccharomyces cerevisiae
• Alignment Length: 659
• Identity: 133/659 - (20%)
• Similarity: 216/659 - (32%)
• Gaps: 207/659 - (31%)

  Fly   159 STTIGGSPLAREFRATAKMAQVIQRFGGSMEGRIDEHPENGSAGCSP---PELSTQQQLEALQAN 220
            |..:|.|....|..|...:.::||:.....              .||   |..|.|..:..|.:.
Yeast   322 SRLLGNSVFNWEILAIPGLMRLIQKMAFKY--------------LSPVLLPPFSLQLNIPQLLSK 372

  Fly   221 --------ELRRKREAQLRQFVFFQLRVHLKSGSDLVAMDKNGLSDPYVKFKVGGRLLHKSRTIH 277
                    |::.|....||:               ||.|.|..: |||:.|::.|:::.|::...
Yeast   373 TGLPIGVLEIKVKNAHGLRK---------------LVGMIKKTV-DPYLTFELSGKIVGKTKVFK 421

  Fly   278 RDLNPVWDEVFIVPIEDPFQPIIVKVFDYDWGLQDDFMGSAKLDLTQLELG---KAEDIHLQLCD 339
            ...||||:|...:.::....|:.:.|:|....|.|..||:...:|.:|...   |.|.:|..
Yeast   422 NSANPVWNESIYILLQSFTDPLTIAVYDKRETLSDKKMGTVIFNLNKLHANHYHKNEKVHFL--- 483

  Fly   340 SSGNGGSGLGEILINLTLWPRSQEDKEMHFQRNSKLAESSKRLKSQIWSSVVTILLVKAKDLPLA 404
               .....:||:..:|..:|..:.         .||....:.....:.:.:..|.:.:.|.|
Yeast   484 ---RNSKPVGELTFDLRFFPTIEP---------KKLLNGDEEPLPDMNTGITKITIRELKGL--- 533

  Fly   405 EDGSKLNDTHFKFRLGNEKY----------KSKSSWTERWLEQFDLHLFDEDQNLEIALWNRNTL 459
               .:|:|..|.|.   |.|          |.|.:...:|  ..|.:....|:...|..:.....
Yeast   534 ---DELSDKKFVFA---ELYVNAELVMTTKKEKRTAHLKW--NSDYYSVVTDRRKTICRFVLKDQ 590

  Fly   460 YGKAIIDLSV------FQRENTHGIWKPLEDCPGEVHLMLTISGTTALETIS-DLKAFKEDPREA 517
            .|| :|..||      ..|...:..|.||.:..||:.:      ||....:. ||
Yeast   591 SGK-VISSSVQPLNHLIDRTEVNKEWIPLRNGKGELKV------TTYWRPVDIDL---------- 638

  Fly   518 QLLRERYKFLRCLQNLRDVGHLT----VKVF--GATGLAAADIGGKSDPFCVLEL-GNARLQTQT 575
                          .|:.||:.|    ::||  .|..|...|..||..|:..:.: |.||.:|..
Yeast   639 --------------GLKSVGYTTPIGMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNE 689

  Fly   576 EYKTLTPNWNKIFTFNVKDITQVLEITVFDEDR---DHRV------------------------- 612
            ..:||.|.||:....:|....|.:.|..|..|.   ||.:
Yeast   690 RIETLNPIWNQSIYVSVTSPLQKVSIDCFGIDTNGDDHNLGSLNIQTQNIYHKDNDDKYTIFIDN 754

  Fly   613 -----EFLGKL--------------VIPLLRIKSG-------------VKRWYTLKDKNLCVRAK 645
                 ..:||.              |:|:|.::..             .|:..||.|||:....|
Yeast   755 APRTGNLIGKKGVKGTVTYYLSFYPVVPVLSLEEAKEVDEINEKKDKLEKQKSTLDDKNISKEEK 819

  Fly   646 GNSPQIQLELTVVWSEIRAVCRALQPKEEKLIQQEAKFK---RQLFLRNVNRLKEIIM--DILDA 705
            ....:.:..||                 ||......|.|   .:|...|...|...::  ::...
Yeast   820 ERIKKEEFRLT-----------------EKYDMYSYKMKLDLDELLQYNAGVLGVTVLGGELPQP 867

  Fly   706 ARYVQSCFE 714
            ..|||:.|:
Yeast   868 GLYVQTFFD 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	30/122 (25%)
		C2B_MCTP_PRT	390..497	CDD:176022	26/122 (21%)
		C2C_MCTP_PRT	537..658	CDD:176023	40/187 (21%)
		PRT_C	<789..893	CDD:285560
TCB2	NP_014312.1	COG5038	4..1178	CDD:227371	133/659 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2311
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940