Protein Alignment Mctp and TCB3

DIOPT Version :9

• Sequence 1: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_013639.1
• Gene: TCB3 / 854903
• SGDID: S000004537
• Length: 1545
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 105/473 - (22%)
• Similarity: 185/473 - (39%)
• Gaps: 112/473 - (23%)

  Fly   248 LVAMDKNGLS--DPYVKFKVGGRLLHKSRTIHRDL-NPVWDEVFIVPIEDPFQPIIVKVFDYDWG 309
            ::..|.:|:.  |||....:..|:|:|| ..|.|. :|::|....|||..|.|.:.::..||...
Yeast   808 IIKGDLSGVGDVDPYYTVSLNRRVLYKS-IYHSDTDHPIFDNSTYVPIFSPNQILTLEFHDYQKI 871

  Fly   310 LQDDFMGSAKLDLTQL------------ELGKAEDIHLQLCDSSGNGGSGL-------------- 348
            .:|.|:||.::..:.:            ..||.|...|:|.|........:
Yeast   872 GKDRFIGSVQIPTSNVFKKDPKSGKYVGNNGKEEISKLKLKDHEHKVTESIVNVSTTFIPINLVY 936

  Fly   349 -GEILINLTLWPRSQEDKEMHFQRNSKLAESSKRLKSQIWSSVVTILLVKAKDLPLAEDGSKLND 412
             .|.|:|:....:..::|:..|:...:..|.......:.|.      :.:.:| |...|..|:|.
Yeast   937 SPEELVNVEKLEKELKEKKKKFEATQEENEQEMEKNPKEWE------VAEIED-PFDSDEKKINR 994

  Fly   413 THFKFRLG-NEKYKSKS------------SWTERWLEQFDLHLFDED---------------QNL 449
               |.:|. ||..|.||            |.:..:||     :..:|               .|.
Yeast   995 ---KAKLSLNELIKQKSGILSMQILEGTLSPSSAYLE-----ILADDISYPVFICMKPSQGKLNS 1051

  Fly   450 EIA-LWNRNTLYGKAIIDLSVFQRENTHGIWKPLEDCPGEVHLMLTISGTTALETISDLKAFKED 513
            |:| ::.|:..|.|.     .|:....| |.|..:|...|          |:..|:..||...|:
Yeast  1052 EMANIFIRDLNYSKL-----HFRVSKKH-IAKDSDDVISE----------TSYSTLKLLKQAYEE 1100

  Fly   514 PR----EAQLLRERYKF------LRCLQNLRDVGHLTVKVFGATGLAAADIGGKSDPFCVLELGN 568
            |.    ....::.|:.:      |...:::.|.|:|.:|:....||.:||..|.||||..:.:.:
Yeast  1101 PMWLNFNGSKMKVRFLYTPTSVKLPSSESVEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFVND 1165

  Fly   569 ARL-QTQTEYKTLTPNWNKIFTFNV--KDITQVLEITVFDEDRDHRVEFLGKLVIPLLRIKSG-V 629
            .:: ::..:.|||.|.||:.....:  :...||: ..|.|.||....:.||:..:.:..::.| .
Yeast  1166 KKVFKSNIKKKTLDPVWNEDAKIPILSRSKNQVI-FNVLDWDRAGDNDDLGQASLDVSSLEVGKT 1229

  Fly   630 KRWYTLKDKNLCVRAKGN 647
            ..|      ||.:..:|:
Yeast  1230 YNW------NLNLNTQGS 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	33/138 (24%)
		C2B_MCTP_PRT	390..497	CDD:176022	28/135 (21%)
		C2C_MCTP_PRT	537..658	CDD:176023	31/115 (27%)
		PRT_C	<789..893	CDD:285560
TCB3	NP_013639.1	COG5038	44..1335	CDD:227371	105/473 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I2507
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2311
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940