DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mctp and AT1G51570

DIOPT Version :9

Sequence 1:	NP_001261078.1	Gene:	Mctp / 37165	FlyBaseID:	FBgn0034389	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_175568.1	Gene:	AT1G51570 / 841582	AraportID:	AT1G51570	Length:	776	Species:	Arabidopsis thaliana

Alignment Length:	788	Identity:	173/788 - (21%)
Similarity:	318/788 - (40%)	Gaps:	181/788 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 LRVHLKSGSDLVAMDKNGLSDPYVKFKVGGRLLHKSRTIH--RDLNPVWDEVFIVP---IEDPFQ 297
            |.|.:....:|...|..|..||||:.|:|.   ::..|.|  :..||.|::||...   ::..:.
plant    41 LYVRVVKAKELPGKDLTGSCDPYVEVKLGN---YRGTTRHFEKKSNPEWNQVFAFSKDRVQASYL 102

  Fly   298 PIIVKVFDYDWGLQDDFMGSAKLDLTQLELGKAEDIHL-----QLCDSSGNGGSGLGEILINLTL 357
            ...||..|.   ::||.:|....||.::......|..|     :|.|  |.|....||::  |.:
plant   103 EATVKDKDL---VKDDLIGRVVFDLNEIPKRVPPDSPLAPQWYRLED--GKGQKVKGELM--LAV 160

  Fly   358 WPRSQEDKEMHFQRNSKLA-----ESSKRLKSQIWSS----VVTILLVKAKDLPLAEDGSKLNDT 413
            |..:|.|:......:|..|     ::...::|:::.|    .:.:.:::|:|| :..|..:..:.
plant   161 WFGTQADEAFPEAWHSDAATVSGTDALANIRSKVYLSPKLWYLRVNVIEAQDL-IPSDKGRYPEV 224

  Fly   414 HFKFRLGNEKYKSKSS--------WTERWL----EQFD--LHLFDEDQNLEIALWNRNTLYGKAI 464
            ..|..:||:..:::.|        |.|..:    |.|:  |.|..||:    ...|::.:.|:..
plant   225 FVKVIMGNQALRTRVSQSRSINPMWNEDLMFVVAEPFEEPLILSVEDR----VAPNKDEVLGRCA 285

  Fly   465 IDLSV----FQRENTHGIWKPLE-------------DCPGEVHLMLTISG-----TTALETISDL 507
            :.|..    |.....:..|..||             ....::|:.:.:.|     ..:....|||
plant   286 VPLQYLDKRFDYRPVNSRWFNLEKHVIMEGGEKKEIKFASKIHMRICLEGGYHVLDESTHYSSDL 350

  Fly   508 KAFKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGL--AAADIGGK--SDPFCVLELGN 568
            :     |...||.:.            ::|.|.:.|..||||  ..|..||:  :|.:||.:.|.
plant   351 R-----PTAKQLWKP------------NIGVLELGVLNATGLMPMKAKEGGRGTTDAYCVAKYGQ 398

  Fly   569 ARLQTQTEYKTLTPNWNKIFTFNVKDITQVLEITVFDE------------DRDHRVEFLGKLVI- 620
            ..::|:|...:.||.||:.:|:.|.|...|:.:.|||.            .:|.|:   ||:.|
plant   399 KWIRTRTIIDSFTPRWNEQYTWEVFDPCTVVTVGVFDNCHLHGGDKNNGGGKDSRI---GKVRIR 460

  Fly   621 --------------PLLRI-KSGVKRWYTLKDKNLCVRAKGNS-------------PQIQLELTV 657
                          |||.: .||||:   :.:.:|.||...:|             |::.....:
plant   461 LSTLEADRVYTHSYPLLVLHPSGVKK---MGEIHLAVRFTCSSLLNMMYMYSMPLLPKMHYLHPL 522

  Fly   658 VWSEIRAV-CRALQPKEEKLIQQEAKFKRQLF------------LR----NVNRLKEIIMDILDA 705
            ..|::..: .:|.|....:|.:.|...::::.            :|    |..|:..::..|:..
plant   523 TVSQLDNLRHQATQIVSTRLTRAEPPLRKEVVEYMLDVGSHMWSMRRSKANFFRIMGVLSGIIAV 587

  Fly   706 ARYVQSCFEWESPVRSSIAFVFWIVACVYGDLETVPLVLLLIILKNWLVR--------LITGTTD 762
            .::.:....|::|:.:.:..:.:|:..:|.:|....:.|.|.::..|..|        :.|..:.
plant   588 GKWFEQICVWKNPITTVLIHILFIILVIYPELILPTIFLYLFLIGVWYYRWRPRHPPHMDTRLSH 652

  Fly   763 A-AAHYDYEYDEDDDDDKEKEEKKSIKERLQAIQEVSQTVQNTIGYLASLGESTINTFNFSVPEL 826
            | :||.| |.||:.|..........::.|...::.::..:|..:|.||:.||...:..::..|..
plant   653 ADSAHPD-ELDEEFDTFPTSRPSDIVRMRYDRLRSIAGRIQTVVGDLATQGERFQSLLSWRDPRA 716

  Fly   827 TWLAVVLLLGAILVLHFVPLRWLLLFWGLMKFSRRLLRPNTIPNNELLDFLSRVPDNEEINQYRE 891
            |.|.|:..|.|.::|:..|.:.:....||.......||..          |..||    :|.:|.
plant   717 TALFVLFCLIAAVILYITPFQVVAFAIGLYVLRHPRLRYK----------LPSVP----LNFFRR 767

  Fly   892 LPPSAPTD 899
            ||  |.||
plant   768 LP--ARTD 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	35/128 (27%)
		C2B_MCTP_PRT	390..497	CDD:176022	24/137 (18%)
		C2C_MCTP_PRT	537..658	CDD:176023	44/165 (27%)
		PRT_C	<789..893	CDD:285560	24/103 (23%)
AT1G51570	NP_175568.1	C2B_MCTP_PRT_plant	40..164	CDD:176024	36/132 (27%)
		C2C_MCTP_PRT_plant	202..352	CDD:175986	28/159 (18%)
		C2D_MCTP_PRT_plant	364..493	CDD:176025	38/134 (28%)
		PRT_C	621..776	CDD:337028	42/170 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1886
OMA	1	1.010	-	-		QHG59961
OrthoDB	1	1.010	-	-		D234298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101057
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.880