DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mctp and AT1G04150

DIOPT Version :9

Sequence 1:	NP_001261078.1	Gene:	Mctp / 37165	FlyBaseID:	FBgn0034389	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_171911.1	Gene:	AT1G04150 / 839249	AraportID:	AT1G04150	Length:	1012	Species:	Arabidopsis thaliana

Alignment Length:	986	Identity:	199/986 - (20%)
Similarity:	374/986 - (37%)	Gaps:	256/986 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 NNLRHRWSRAKSKDRLGRKSPSDFLEESTDYAADYSSEGSSV----THSPRHRSTTIGGSPLARE 170
            |:|||:.......:.....:..:||.:.....:....||.||    |...|...:::.|....:.
plant    70 NDLRHKALEINVYNEKRSSNSRNFLGKVRVLGSSVGREGESVVQLYTLEKRSLFSSVRGEISVKH 134

  Fly   171 FRAT----AKMAQVIQRFGGSMEGRIDEHPENGSAGCSPPELSTQQQLEAL-----QANELRRKR 226
            :..|    .:..:.:.|.|||.:.:   ..:|.|:..:..:...|||.:..     :.|:.:.::
plant   135 YMTTTAENGENVRRVNRSGGSKKSK---KVQNVSSSMAIQQQQQQQQQQISLHNHNRGNQQQSQQ 196

  Fly   227 EAQ-LRQFVFFQLRVHLK----------------------SGSDLVAMDK---------NGLSDP 259
            ..| .|...|:..:..:|                      :||...::.:         |||
plant   197 NGQGQRMLPFYPHQSEIKPLVITALPSPMPGPGPRPIVYSNGSSEFSLKETKPCLGGTSNGL--- 258

  Fly   260 YVKFKVGGRLLHKSRTIH------------------RDL-------------------------- 280
                  ||...||.:|..                  :||
plant   259 ------GGLSSHKDKTSSTYDLVEQMQYLYVNIVKAKDLSVLGEVVSEVKLGNYRGVTKKVSSNS 317

  Fly   281 -NPVWDEVFIVPIEDPFQPIIVKVFDYDWGLQDDFMGSAKLDLTQLELGKAEDIHLQ---LCDSS 341
             ||.|::||:.. ::..|..:|::|..: |.:|::.|....||:::......|..|.   ....:
plant   318 SNPEWNQVFVFS-KERIQSSVVELFVKE-GNKDEYTGRVLFDLSEIPTRVPPDSPLAPQWYKIEN 380

  Fly   342 GNGGSGLGEILINLTLWPRSQEDKEM----HFQRNSKLAESSKRLKSQIWSS----VVTILLVKA 398
            .|||.|.||:::  ::|..:|.|:..    |.:..:...|....:||:::.|    .:.|.:::|
plant   381 RNGGRGNGELMV--SVWFGTQADEAFAEAWHSKAGNVHIEELSSIKSKVYLSPKLWYLRISVIEA 443

  Fly   399 KDLPLAEDGSKL---NDTHFKFRLGNE------------KYKSKSSWTERWL----EQFD--LHL 442
            :|:.:.:.||.|   .:...|.::|::            |..|...|.|..:    |.|:  :.:
plant   444 QDVAIMDKGSSLMRFPELSAKLQVGSQILRTAIASAIPTKSFSNPYWNEDLMFVVAEPFEDCVTV 508

  Fly   443 FDEDQNLEIALWNRNTL-YGKAIIDLSVFQRENTHGI----WKPLED------CPGEVHLMLTIS 496
            ..||:....|:..:|.: .|:..|.:|..:|.....:    |..|::      ....:||.|::.
plant   509 VVEDRLNGGAIGGQNDVAVGRVQIPISAVERRTGDTLVGSRWFSLDNGNNNNRFGSRIHLRLSLD 573

  Fly   497 GTTALETISDLKAFKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAAADI-----GG 556
            |  ....:.:...:..|.|..  .:|.:|        ..||.|.:.:..||||....:     ||
plant   574 G--GYHVLDEATMYNSDVRPT--AKELWK--------PQVGLLEIGILSATGLMPMKVRDGKCGG 626

  Fly   557 KSDPFCVLELGNARLQTQTEYKTLTPNWNKIFTFNVKDITQVLEITVFD-----EDRDHRVEFLG 616
            .:|.:||.:.|...::|:|...:|.|.||:.:|:.|.|...|:.:.|||     |:.:.|...:|
plant   627 IADSYCVAKYGPKWVRTRTVVDSLCPKWNEQYTWEVYDPCTVVTVGVFDNARVNENNNSRDVRIG 691

  Fly   617 KLVIPLLRIKSGVKRWYT---------------LKDKNLCVRAK-GNS------------PQI-- 651
            |:.|.|..:::|  |.||               ..:.:|.||.. ||:            |::
plant   692 KVRIRLSTLETG--RVYTHSYPLIVLHPSGVKKTGELHLAVRLSCGNAVNMLHMYALPLLPKMHY 754

  Fly   652 -------QLELTVVWSEIRAVCRALQPKEEKLIQQEAKF--------------KRQLFLRNVNRL 695
                   .|| .:.:..:.||...|...|..|.::..::              |...|     ||
plant   755 TQPLGVHMLE-RLRYQTLNAVAARLSRAEPPLGREVVEYMLDHDFHVWSMRRSKANFF-----RL 813

  Fly   696 KEIIMDILDAARYVQSCFEWESPVRSSI---AFVFWIVACVYGDLETVPLVLLLIILKNWLVR-- 755
            ..:|..::..|:.|:....|..||.|::   ||:|.:   ::.:|....|:|....:..|..|
plant   814 VNVISGLVAVAKLVEVMRSWSKPVYSTVFVLAFLFMV---LFPELLLPCLLLYTAAVGVWRFRRR 875

  Fly   756 ------LITGTTDAAAHYDYEYDEDDDDDKEKEEKKSIKERLQAIQEVSQTVQNTIGYLASLGES 814
                  :....:.|...:..|.||:.|..........::.|...::.::..||..:|.:||.||.
plant   876 SRYPPHMDARISHAETVFPDELDEEFDTFPTSRGFDVVRMRYDRVRSIAGRVQTVVGDMASQGER 940

  Fly   815 TINTFNFSVPELTWLAVVLLLGAILVLHFVPLRWLLLFWGLM-----KFSRRLLRPNTIPNNELL 874
            .....::..|..|:|.::..|.|.:..:.||::..:...||.     :|.|:|      |:.. |
plant   941 VQALLSWRDPRATFLFLMFCLLAAVGFYTVPVKLTVAISGLYYLRPPRFRRKL------PSRG-L 998

  Fly   875 DFLSRVPDNEE 885
            .|..|:|...:
plant   999 SFFRRLPSRAD 1009

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	34/198 (17%)
		C2B_MCTP_PRT	390..497	CDD:176022	27/138 (20%)
		C2C_MCTP_PRT	537..658	CDD:176023	43/167 (26%)
		PRT_C	<789..893	CDD:285560	25/102 (25%)
AT1G04150	NP_171911.1	C2A_MCTP_PRT_plant	12..138	CDD:175989	13/67 (19%)
		C2B_MCTP_PRT_plant	280..398	CDD:176024	24/121 (20%)
		C2C_MCTP_PRT_plant	435..591	CDD:175986	29/157 (18%)
		C2D_MCTP_PRT_plant	603..729	CDD:176025	34/127 (27%)
		PRT_C	863..1012	CDD:337028	32/154 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1886
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D234298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101057
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870