DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mctp and AT3G03680

DIOPT Version :9

Sequence 1:	NP_001261078.1	Gene:	Mctp / 37165	FlyBaseID:	FBgn0034389	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_187018.1	Gene:	AT3G03680 / 821190	AraportID:	AT3G03680	Length:	1017	Species:	Arabidopsis thaliana

Alignment Length:	881	Identity:	191/881 - (21%)
Similarity:	317/881 - (35%)	Gaps:	253/881 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 PENGSAGCSPP-ELST---QQQLEALQANELRRKREAQLRQFVFFQLRVHLKSGSDL----VAMD 252
            |:...|...|| |:..   .|:.|.::.|||..|.|...||.:.         ||||    :..|
plant   212 PDTAVAPPPPPAEVKNPPIPQKAETVKQNELGIKPENVNRQDLI---------GSDLELPSLTRD 267

  Fly   253 KN-----GLSD--PYVKFKVGGRLLHKSRTIHRD-LNPV--------------------WDEVFI 289
            :|     .|.|  |::..:|.     |::....| .|||                    ||:||.
plant   268 QNRGGGYDLVDRMPFLYIRVA-----KAKRAKNDGSNPVYAKLVIGTNGVKTRSQTGKDWDQVFA 327

  Fly   290 VPIED-PFQPIIVKVF--------DYDWGLQDDFMGSAKLDLTQLELGKAED-------IHLQLC 338
            ...|. ....:.|.|:        |......:..:|:...||.::......|       ..|:..
plant   328 FEKESLNSTSLEVSVWSEEKIEKEDKTTTTTESCLGTVSFDLQEVPKRVPPDSPLAPQWYTLESE 392

  Fly   339 DSSGNGGSGLGEILINLTLWPRSQEDKEMH--FQRNS--KLAESSKR--LKSQIWSSVVTILLVK 397
            .|.||.        :.|.:|..:|.|:...  :|.:|  .:.|:..:  |..::|...:|:  ::
plant   393 KSPGND--------VMLAVWLGTQADEAFQEAWQSDSGGLIPETRSKVYLSPKLWYLRLTV--IQ 447

  Fly   398 AKDLPL---AEDGSKLNDT--HFKFRLGNEKYK-----------SKSSWTERWLEQFDLHLFDED 446
            .:||.|   :|..||:..|  :.|.:||.:.:|           |..|....|.|  || :|...
plant   448 TQDLQLGLGSEAKSKIPTTELYVKAQLGPQVFKTARTSIGPSASSSGSGNPTWNE--DL-VFVAS 509

  Fly   447 QNLEIAL-------WNRNTLYGKAIIDLSVFQREN-----THGIW--------KPLEDCPGEVHL 491
            :..|..|       .|..:: |:..|.:...:|.|     ....|        ||..   |.:|:
plant   510 EPFEPFLIVTVEDITNGQSI-GQTKIHMGSVERRNDDRTEPKSRWFNLAGDEKKPYS---GRIHV 570

  Fly   492 MLTISG-----TTALETISDLKAFKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAA 551
            .:.:.|     ..|....||::     |...||.:.            .:|.|.|.:.|||.|..
plant   571 KVCLEGGYHVLDEAAHVTSDVR-----PSAKQLAKP------------PIGLLEVGIRGATNLLP 618

  Fly   552 A----DIGGKSDPFCVLELGNARLQTQTEYKTLTPNWNKIFTFNVKDITQVLEITVFDEDRDHRV 612
            .    ...|.:|.:.|.:.|...::|:|......|.||:.:|::|.|...||.|.|||..|..|.
plant   619 VKTRDGTRGTTDAYVVAKYGPKWIRTRTILDRFNPRWNEQYTWDVYDPCTVLTIGVFDNGRYKRD 683

  Fly   613 EF--------LGKLVIPL----------------LRIKSGVKRWYTLKDKNLCVRAKGNSPQ--- 650
            |.        :||:.:.|                :.:.||.|:   :.:..:.||.  :.|.
plant   684 ESGKQGRDVRVGKIRVRLSTLDMNRIYLNSYTLTVILPSGAKK---MGEVEIAVRF--SCPSWLS 743

  Fly   651 -IQLELTVVWSEIRAVCRALQPKEEKLIQQEAKFKRQLFLRNVN-RL--------KEIIMDILDA 705
             ||..:|.:...:..| |.|.|.::.:::..|       :|.|. ||        :|::..:||.
plant   744 IIQAYVTPMLPRMHYV-RPLGPAQQDILRHTA-------MRIVTARLARSEPPLGQEVVQYMLDT 800

  Fly   706 ---------------------------ARYVQSCFEWESPVRSSIAFVFW--IVACVYGDLETVP 741
                                       ||::.....|..|..:.:..:..  ||.|.:..|.||.
plant   801 DNHVWSMRRSKANWFRVITFLSRAATIARWIHGIRTWVHPPTTVLVHLLLVAIVLCPHLVLPTVF 865

  Fly   742 LVLLLIILKNWLVR---LITGTTDAAAHYDY----EYDEDDDDDKEKEEKKSIKERLQAIQEVSQ 799
            :...||:...:..|   .:.......:..|.    |.||:.|......:.:.::.|...::.::.
plant   866 MYAFLILALRFRYRGRVKVNSVDPRLSCVDSVAPDELDEEFDGFPTTRQPEVVRIRYDRLRALAG 930

  Fly   800 TVQNTIGYLASLGESTINTFNFSVPELTWLAVVLLLGAILVLHFVPLRWLLLFWGLMKFSRRLLR 864
            ..|..:|.:|:.||.....||:..|..|.:.||..|.|..:.:.||.:..||..|.........|
plant   931 RAQTLLGDVAAQGERVEALFNWRDPRATCIFVVFCLFASFLFYIVPFKVFLLGSGFYYIRHPRFR 995

  Fly   865 PNTIPNNELLDFLSRVPDNEEINQYRELPPSAPTDQ 900
                      |.:..||    :|.:|.||  :.:||
plant   996 ----------DDMPSVP----VNFFRRLP--SMSDQ 1015

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	32/167 (19%)
		C2B_MCTP_PRT	390..497	CDD:176022	31/142 (22%)
		C2C_MCTP_PRT	537..658	CDD:176023	40/152 (26%)
		PRT_C	<789..893	CDD:285560	25/103 (24%)
AT3G03680	NP_187018.1	C2	8..134	CDD:301316
		C2B_MCTP_PRT_plant	282..407	CDD:176024	24/137 (18%)
		C2C_MCTP_PRT_plant	440..593	CDD:175986	35/166 (21%)
		C2D_MCTP_PRT_plant	605..733	CDD:176025	33/130 (25%)
		PRT_C	861..1017	CDD:285560	40/171 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1886
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D234298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101057
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870