Protein Alignment Mctp and esyt2a

DIOPT Version :9

• Sequence 1: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: XP_005171454.1
• Gene: esyt2a / 570012
• ZFINID: ZDB-GENE-070912-588
• Length: 922
• Species: Danio rerio
• Alignment Length: 461
• Identity: 92/461 - (19%)
• Similarity: 165/461 - (35%)
• Gaps: 177/461 - (38%)

  Fly   238 LRVHLKSGSDLVAMDK------NGLSDPYVKFKVGGRLLHKSRTIHRDLNPVWDEVFIVPIED-P 295
            ||||...|.||::.|.      .|.||||...::..:|. :|:.|...|||.|:||:...:.| .
Zfish   328 LRVHFLEGQDLLSKDTYMGGLIKGKSDPYGVIQINNQLF-RSKIIKDSLNPRWNEVYEAIVYDGQ 391

  Fly   296 FQPIIVKVFDYDWGLQDDFMGSAKLDLTQLELGKAEDIHLQLCDSSGNGGSGLGEILIN---LTL 357
            .|.:.:::||.|.. .|||:||..:::.:::..:..|....|.      |...|::.:.   |:|
Zfish   392 GQVVFIELFDEDTD-HDDFLGSLTMEIDEIQKQQKVDEWFDLI------GVPNGKLHVKAEWLSL 449

  Fly   358 WPRSQEDKEMHFQRNSKLAESSKRLKSQ----IWSSVVTILLVKAKDLPLAEDGSKLNDTHFKFR 418
            .|...:..|        :..|.|..|.|    :.|:::.:.|..||:||...:|          :
Zfish   450 HPTPDKLDE--------VLSSIKADKGQANDGLSSALLLVHLDSAKNLPGVFEG----------Q 496

  Fly   419 LGNEKYKSKSSWTERWLEQFDLHLFDEDQNLEIALWNRNTLYGKAIIDLSVFQRENTHGIWK--- 480
            :|:...:.:.|                                     ..:...|||..:::
Zfish   497 VGSGCLRERRS-------------------------------------AGLVFCENTSALYRTMF 524

  Fly   481 --PLEDCPGEVHLMLTISGTTALETISDLKAFKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKV 543
              |||
Zfish   525 RNPLE------------------------------------------------------------ 529

  Fly   544 FGATGLAAADI-----GGKS-----DPFCVLELGNARLQTQTEYKTLTPNWNKIFTF---NVKDI 595
            |.:.||....:     .||.     :||....:|:...:::|.:||:.|.|.:.|||   |.|
Zfish   530 FNSAGLKKGAVNKAVKSGKKVTSVPNPFVQFTVGHRSFESKTRFKTIEPVWEETFTFLIHNPK-- 592

  Fly   596 TQVLEITVFDEDRDHRVEFLGKLVIPLLRIKSGVKRWYTLKDKNLCVRAK--------GNSPQIQ 652
            .|.||:.|.||..:..   ||.:.:||.::         ||:|.:.:..:        |::.:::
Zfish   593 CQDLEVEVKDEKHECS---LGTITLPLSQL---------LKEKQMTMSQRFPLKNSGPGSTLKMK 645

  Fly   653 LELTVV 658
            :.|.::
Zfish   646 MALRIL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	37/128 (29%)
		C2B_MCTP_PRT	390..497	CDD:176022	14/111 (13%)
		C2C_MCTP_PRT	537..658	CDD:176023	33/141 (23%)
		PRT_C	<789..893	CDD:285560
esyt2a	XP_005171454.1	SMP_LBD	132..310	CDD:293652
		C2A_C2C_Synaptotagmin_like	326..446	CDD:176037	36/125 (29%)
		C2B_Synaptotagmin-like	548..638	CDD:176015	27/103 (26%)
		PRK13733	<642..>723	CDD:184285	1/10 (10%)
		C2C_KIAA1228	788..913	CDD:175996

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2311
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940