Protein Alignment Mctp and esyt3

DIOPT Version :9

• Sequence 1: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_001116705.1
• Gene: esyt3 / 553238
• ZFINID: ZDB-GENE-050809-35
• Length: 861
• Species: Danio rerio
• Alignment Length: 769
• Identity: 151/769 - (19%)
• Similarity: 259/769 - (33%)
• Gaps: 295/769 - (38%)

  Fly   341 SGNGGSGLGEILINL---TLWPRSQEDKEMHFQRNSKLAESSKRLKSQIWSSVVTILLVKAKDLP 402
            :|..|..:..||:::   |:|..::..||..........|:.|        .|::..| ||.|:|
Zfish    47 TGTFGLSVSWILLSMFMWTMWKNNRRWKEQRIDTAIDFLENEK--------DVISTEL-KAMDMP 102

  Fly   403 LAEDGSKLNDTHFKFRLGNEKYKSKSSWTERWLEQ----FDLHL--------------------- 442
                    ...||       ....|::|..:.|:|    |.:::
Zfish   103 --------PWIHF-------ADVEKAAWINKILQQSWPFFGVYMEKLLIENIQTVVRSVHPHLKT 152

  Fly   443 ---------------------FDEDQNLEIALWNRNTLYGKAIIDLSV----------------- 469
                                 .||.:..|:.| :.|.:| :|.:|:..
Zfish   153 FTFTKVHMGQKAPTITGIRAYTDELETREVIL-DLNIVY-EADVDIDADVNRAIKVGIKGLQLQG 215

  Fly   470 ----------------------FQRE-----NTHGIWKPLEDCPGEVHLMLTISGTTALETISDL 507
                                  |.|.     |..|:...| |.||..||    |.:..::.|:.|
Zfish   216 MLRVILEPLIGQAPLVGGVTMFFIRRPALQINWTGVTNVL-DGPGLSHL----SESAIVDVIASL 275

  Fly   508 KAFKED---PREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAAAD------IGGKSDPFCV 563
            ......   |...|:..|:.:|      ....|.:.|.|..|..|.|.|      :.|||||:.|
Zfish   276 MVLPNRMCFPLIDQVKVEQMRF------PLPRGVVRVHVLEARDLVAKDSHMMGLVKGKSDPYTV 334

  Fly   564 LELGNARLQTQTEYKTLTPNWNKIFTFNVKDIT-QVLEITVFDEDRDHRVEFLGKLVIPL--LRI 625
            |.:||...:|:|..:||.|.||:::.|.:.:.. |.||:.::|||:| ..:|||:..:..  :|.
Zfish   335 LRVGNKHFKTKTIKETLNPRWNEVYEFVIHEAPGQELEVELYDEDKD-ADDFLGRFSMDCGDVRK 398

  Fly   626 KSGVKRWYTLKD------------KNLCVRAKGNSPQIQLE----LTVVWSEIRAVCRALQPKEE 674
            ...:.:||||:|            .:||     ::|::..|    |......:...|.:..||::
Zfish   399 DREIDKWYTLEDIESGQIHFKLQWFSLC-----SNPELLKETSDGLACAMLALYLDCASNLPKDQ 458

  Fly   675 KLIQQEAKFKRQ-------LFLRNVNRLKEIIMDILDAARYVQSCFEWESPVRSSIAFVFWIVAC 732
            :.:....|..:|       ....|.|...|..:|:......|  .|..:.|:... .|.|::.:
Zfish   459 REVTHNEKHGKQPKESRVTRKTNNPNSYVEFSIDLQSQKSKV--VFASKDPIFDE-CFTFFVHS- 519

  Fly   733 VYGDLETVPLVLLLIILKNWLVRLITGTTDAAAHYDYEYDEDDDDDKEKEEKKSIKERLQAIQEV 797
                            :||.::.:                     :.::.||||
Zfish   520 ----------------VKNQVLNV---------------------EVKEHEKKS----------- 536

  Fly   798 SQTVQNTIGYLASLGESTINTFNFSVPELTWLAVVLLLGAILVLHFVPLRWLLLFWGLMKFSRRL 862
                        |||:       ||:|      :|.||..                ..|...:|.
Zfish   537 ------------SLGK-------FSLP------LVRLLNV----------------SDMTLDQRF 560

  Fly   863 LRPNTIPNNEL-LDFLSRVPDNEEINQYRELPPSAPTDQTRNNPKKKLKGSXSITSADAAMASLS 926
            ....:.||::: |..:.|:...|:  |..::..|||.|:..:.|.:....:.:.||        :
Zfish   561 QLERSAPNSQVKLKAVLRILTLEK--QQPKVVTSAPQDKNTSTPNRPEPRTPNPTS--------N 615

  Fly   927 PLQSSALGGAAGGSGSGSGYGGRQQQLMQRFRANTSQLKHKFGQAKSLSLSHSE 980
            |:.:.|...||.             ||:|      |..|.| |...|:.||.::
Zfish   616 PVPNPAPPPAAA-------------QLVQ------SNPKEK-GPISSVPLSKTQ 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	4/18 (22%)
		C2B_MCTP_PRT	390..497	CDD:176022	31/196 (16%)
		C2C_MCTP_PRT	537..658	CDD:176023	45/145 (31%)
		PRT_C	<789..893	CDD:285560	17/104 (16%)
esyt3	NP_001116705.1	SMP_LBD	109..287	CDD:293652	27/184 (15%)
		C2A_C2C_Synaptotagmin_like	302..422	CDD:176037	40/120 (33%)
		C2B_Synaptotagmin-like	443..567	CDD:176015	31/216 (14%)
		C2C_KIAA1228	726..850	CDD:175996

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2311
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940