Protein Alignment Mctp and esyt-2

DIOPT Version :9

• Sequence 1: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_001366808.1
• Gene: esyt-2 / 175882
• WormBaseID: WBGene00020443
• Length: 808
• Species: Caenorhabditis elegans
• Alignment Length: 483
• Identity: 101/483 - (20%)
• Similarity: 182/483 - (37%)
• Gaps: 123/483 - (25%)

  Fly   249 VAMDKNGLSDPYVKFKVGGRLLHKSRTIHRDLNPVWDEVFIVPIED-PFQPIIVKVFDYDWGLQD 312
            ::..|.|.||||.:.:||.:.. |:|||..||||:|:|.|...::. ..|.:.:::||.|.| :|
 Worm   293 ISFIKKGKSDPYAEIQVGSQFF-KTRTIDDDLNPIWNEYFEAVVDQADGQKLRIELFDEDQG-KD 355

  Fly   313 DFMGSAKLDLTQLELGKAEDIHLQLCDSSGNGGSGLGEILINLTLWPRSQEDKEMHFQRNSKLAE 377
            :.:|...:||..::.....|....|      .|...|::.|..|....|.|.:  |.::....||
 Worm   356 EELGRLSVDLKLVQAKGTIDKWYPL------EGCKHGDLHIKATWMNLSTELR--HLEKQEWEAE 412

  Fly   378 SSKRLKSQIWSSVVTILLVKAKDLPLAED------------GSKLNDTHFKFRLGNEKYKSKSSW 430
            ..:..| .|.|:::.:.:....|||..:.            |.:...|..|.:..|..::||..:
 Worm   413 WGQADK-PIHSALLMVYIDSVADLPYPKSKLEPSPFVEVSLGKETQRTPVKVKTVNPLFQSKFLF 476

  Fly   431 TERWLEQFDLHLFDEDQNLEIALWNRNTLYGKAIIDLSVFQRENTHGIWKPLEDCPGEVHLMLTI 495
            ..|.||..:|.....|.....:|.:.|......:.:.::.|.:..|.:...:...|..:...:.:
 Worm   477 FVRHLEGQELKFEAVDDGTRRSLGSLNIPLTTLLKEPNLEQNQQMHMLTLGVHQSPIVITTRIRV 541

  Fly   496 SGTTALETI--SDLKAFKEDP--REAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAAADIGG 556
            ...|..:.|  .:|:..||:.  |...|::.:.|    ..|..::||              |:.|
 Worm   542 LQKTEGDAIKMQELRQEKEEEKLRNNALIQGKPK----KGNNSELGH--------------DVLG 588

  Fly   557 KSDPFCVLELGNARLQTQTEYKTLTPNWNKIFTFNVK--------DITQVLEITVFDED-RDHRV 612
                    |.|||                    |:::        |:..|......::| .|..|
 Worm   589 --------EYGNA--------------------FHIERANGKVNGDVVAVEPAKTVNQDAADDEV 625

  Fly   613 EF---------------------------LGKLVIPLLRIKSGVKRWYTLKDKNLCVRAKGNSPQ 650
            |.                           ||:    |.|.|..:|:..|..|:|     :|.. :
 Worm   626 EIKLNVDNYQMLRSDSQGSLNSHGRSNSRLGR----LFRSKHEMKKRETRADEN-----RGEI-E 680

  Fly   651 IQLELTVVWSEIRAV---CRALQPKEEK 675
            ||::...:.::::..   ||.|...::|
 Worm   681 IQIDFDDLVNQLKIALIRCRDLMTFDKK 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	33/108 (31%)
		C2B_MCTP_PRT	390..497	CDD:176022	19/118 (16%)
		C2C_MCTP_PRT	537..658	CDD:176023	27/156 (17%)
		PRT_C	<789..893	CDD:285560
esyt-2	NP_001366808.1	SMP_LBD	83..260	CDD:293652
		C2A_C2C_Synaptotagmin_like	276..394	CDD:176037	33/108 (31%)
		C2B_Synaptotagmin-like	424..528	CDD:176015	18/103 (17%)
		C2	691..800	CDD:214577	4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910