Protein Alignment Cyp12b2 and cyp27a1.2

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_073769098.1
• Gene: cyp27a1.2 / 795106
• ZFINID: ZDB-GENE-081104-511
• Length: 580
• Species: Danio rerio
• Alignment Length: 476
• Identity: 124/476 - (26%)
• Similarity: 228/476 - (47%)
• Gaps: 37/476 - (7%)

  Fly    39 ADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKP 103
            |...:.:..::.::..::|...:..||...:..|.|.:.:.:|:  ..:::||.::.|..  |..
Zfish   104 ASVSVQDGHRKLKTEADLPEIKIFTMLYQMLFKGYLNSVHELQL--YQKQVYGPLWKINA--GNL 164

  Fly   104 NAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVG-GLASDQGQEWADIRNKVN 167
            ..:...:.:..|...|.:..:|.|..:.....:|.:      :|:. |..:::|::|..:|..:|
Zfish   165 QGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDL------RGISYGPFTEEGEKWYKLRAVLN 223

  Fly   168 PVLMKVQNVRQNLPQLDQISKEFIDKLETQRN-PETHTLTTDFHNQLKMWAFESISFVALNTRMG 231
            ..::..::..|....::.:..:||.::...|. ..|..|.::..|:|..::.|.|:.:...||:|
Zfish   224 KRMLHPKDSVQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLEGIASILFETRIG 288

  Fly   232 LLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMR 296
            .|.........:....:...|.||....:.|: ||......::|::..:|.|....:..|:..|.
Zfish   289 CLEKEIPAETQKFINFIAQMFTYSMHVALLPN-WTRKYFPFWQKYIDGWDGIFKFGTKMIDMKME 352

  Fly   297 GFGKNDDGKTKCV---LEQLLEHNK---KVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQE 355
            ...|..|......   |..||.:.|   |.....|.::|:||:|:||:..|..||.|:::|..||
Zfish   353 AIQKRVDTNQDVAGEYLTYLLSNGKISRKDVYGSVSELLLAGVDSTSNTMLWALYLLSKDPEAQE 417

  Fly   356 KLRRELLRILPTTKDSL--TDQNTKNMPYLRACIKEGLRITSITPGNFR-ITPKDLVLSGYQVPR 417
            .|.:|:.::|   ||..  |.:...:||:|:|.|||.||:..:.|.|.| |...::|:..|..|:
Zfish   418 TLYQEVTKVL---KDDRIPTAEEVNSMPFLKAVIKETLRLYPVVPVNSRLIAETEVVIGEYFFPK 479

  Fly   418 GTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTR-NPFVYLPFGFGPRTCIG 481
            .|...:....:|.|:|.|.:..:|.|||||:.           .||| |||..:|||||.|.|:|
Zfish   480 KTTFTLCHYVISRDEKVFPEPQKFKPERWLRD-----------GRTRPNPFGSIPFGFGVRACVG 533

  Fly   482 KRIAELEIETLLVRLLRSYKV 502
            :||||||:...|.||::.:::
Zfish   534 RRIAELEMHLALARLIKLFEM 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	117/428 (27%)
cyp27a1.2	XP_073769098.1	None