Protein Alignment Cyp12b2 and cyp27a1.3

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_002934001.3
• Gene: cyp27a1.3 / 594905
• XenbaseID: XB-GENE-18386061
• Length: 518
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 132/493 - (26%)
• Similarity: 238/493 - (48%)
• Gaps: 44/493 - (8%)

  Fly    29 TLSQQTQLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDI 93
            |:.::..|.::.:.:.| .:..::..::||||.|::|.:....|.|..|:.:|:  :.::.||.:
 Frog    24 TVRKKATLGVSGATVVE-GKTLKTLDDLPGPSPLKLLYWIFLRGYLFRTHELQV--IFKKTYGPM 85

  Fly    94 YCIPGMMGKPNAVFTY-NPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQ 157
            :   .|..:.:|:.|. :||..|...|.||.:|.|..:    :..:.|| |:.....|..:::|.
 Frog    86 W---KMSDRQHAMVTVASPDLLESLLRKEGKYPTRADM----FIMREHR-DLRGHSYGPVTEEGH 142

  Fly   158 EWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKL-ETQRNPETHTLTTDFHNQLKMWAFESI 221
            :|..||..:|..::|.:........::::..:.:.|: |......:.|........:..:|||||
 Frog   143 QWHRIRTILNQRMLKPRETVVYAGSMNEVVSDLLLKIKELTAQSSSGTQVNGVAELMYKFAFESI 207

  Fly   222 SFVALNTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDI 286
            ..|...||:|.|:....|...:....:.....:.......|. ||......:.::::.:|.|.|.
 Frog   208 CTVLFETRLGCLNKEILPETQKFIDSIGIMLEHLTMLTRLPQ-WTKGILPYWGRYIEAWDTIFDF 271

  Fly   287 TSNYIETAMRGF------GKNDDGKTKCVLEQLLEHNK---KVAVTMVMDMLMAGIDTTSSACLT 342
            ....|:..|...      |:..:|:   .|..||...|   :.....|:::|.||:||||:....
 Frog   272 GKKLIDKKMEDIEGRLKRGEEVEGE---YLTYLLSSGKLSMEEVYGSVVELLQAGVDTTSNTLTW 333

  Fly   343 ILYHLARNPSKQEKLRRELLRILP--TTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFR-IT 404
            .||.|:|||..|..|.:|::|::|  |..||   :....||.|:|.|||.||:..:.|.|.| |.
 Frog   334 ALYQLSRNPEIQNNLYQEVIRVIPGETIPDS---EAIARMPLLKAVIKETLRLFPVVPENARMIN 395

  Fly   405 PKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVY 469
            .|::.:..|..|..|..::|...:|.|:..|.::..|:|||||:.          :....:||..
 Frog   396 EKEVTIKDYVFPVKTQFILGHYAISRDETTFPEADRFLPERWLRD----------SGMKHHPFGS 450

  Fly   470 LPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPE 507
            :|||:|.|.|:|:||||||:...|.|:::.::|  :|:
 Frog   451 IPFGYGVRACVGRRIAELEMHLALSRIIKMFQV--IPD 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	119/435 (27%)
cyp27a1.3	XP_002934001.3	cytochrome_P450	79..508	CDD:477761	119/435 (27%)