Protein Alignment Cyp12b2 and CYP26B1

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_063938.1
• Gene: CYP26B1 / 56603
• HGNCID: 20581
• Length: 512
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 112/517 - (21%)
• Similarity: 204/517 - (39%)
• Gaps: 136/517 - (26%)

  Fly    30 LSQQT-QLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDI 93
            :|||. ||..|.:| |:..:.....|.:..|.:.....:.:.|...:::.        ||.||::
Human    28 VSQQLWQLRWAATR-DKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSR--------REKYGNV 83

  Fly    94 YCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRI-GLESLNYYRKIHRPDVFKGVGGLASDQGQ 157
            : ...::|:|                     .||: |.|::   |||     ..|...|.|   .
Human    84 F-KTHLLGRP---------------------LIRVTGAENV---RKI-----LMGEHHLVS---T 115

  Fly   158 EW-----------------ADIRNKVNPVLMKV---QNVRQNLPQLDQISKEFIDKLETQRNPET 202
            ||                 .||......|..|:   :.:...||::..:.:      :|.|...:
Human   116 EWPRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQ------DTLRAWSS 174

  Fly   203 HTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTF 267
            |....:.:.:.:...|.    :|:...:|.  ..|:.:...|.:..:.|.:..|...|.
Human   175 HPEAINVYQEAQKLTFR----MAIRVLLGF--SIPEEDLGHLFEVYQQFVDNVFSLPVD------ 227

  Fly   268 YKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDGK-----TKCVLEQLLEHNKKVAVTMVMD 327
            ...:|:::.::.    ..|....:|.|:|...:...||     ...::|...||.|::.:..:.|
Human   228 LPFSGYRRGIQA----RQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKD 288

  Fly   328 ----MLMAGIDTTSSACLTILYHLARNPSKQEKLRREL----------------LRILPTTKDSL 372
                ::.|...||:||..:::..|.::|:..||||.||                ||:     |:|
Human   289 GTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRL-----DTL 348

  Fly   373 TDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQ 437
            :     .:.||...|||.:|:.:...|.:|...:...|.|:|:|:|..|:..:.:..:....|..
Human   349 S-----GLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKD 408

  Fly   438 SSEFIPERWLKSDLAPDIQACPAARTRNP---FVYLPFGFGPRTCIGKRIAELEIETLLVRL 496
            .:.|.|:|:.:            ||:.:.   |.|||||.|.|||:||.:|:|.::.|.|.|
Human   409 VNVFDPDRFSQ------------ARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVEL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	103/487 (21%)
CYP26B1	NP_063938.1	p450	23..490	CDD:325183	112/517 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D871849at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010