Protein Alignment Cyp12b2 and cyp27c1

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001106808.2
• Gene: cyp27c1 / 558396
• ZFINID: ZDB-GENE-080204-68
• Length: 540
• Species: Danio rerio
• Alignment Length: 552
• Identity: 139/552 - (25%)
• Similarity: 261/552 - (47%)
• Gaps: 79/552 - (14%)

  Fly     9 IYRNVSGNQLWFNRNSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPS-LLRMLSFFMPGG 72
            ::::|:...|....:|.  ..|.:::.:..|:.  .:|..:.:|..|:|||| :..:|.||...|
Zfish    30 LHKSVASGSLEIAAHSQ--ADLKEESAVSPAEE--VQKAARVKSLKEMPGPSTVANLLEFFYRDG 90

  Fly    73 ALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYR 137
            ..| .:.|||....:  ||.|:  ....|....|...:.|......|:|...|.|..:||...||
Zfish    91 FSR-IHEIQMEHAKK--YGKIF--KSRFGPQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYR 150

  Fly   138 KIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPET 202
            .:.....     ||.|.:|.||..:|:.:..::|:.::|......::.:..:.:.:::|.|:.:.
Zfish   151 DLRGRST-----GLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQD 210

  Fly   203 HTLTT-DFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADR---LAKHMRDFFNYSFQFDVQPS 263
            .:.|. :.::....:|.|.::.:...||:|.| :|..|...:   .|.|:
Zfish   211 DSQTVLNINDLFFKYAMEGVATILYETRLGCL-ENEIPKMSQEYITALHL--------------- 259

  Fly   264 IWTFYKT---AG-------------FKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQ 312
            :::.:||   ||             :::|..::|.:...:..:::..:....|..: |::.:...
Zfish   260 MFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKRLSEIKKQME-KSEEIKGG 323

  Fly   313 LLEH-------NKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRIL----P 366
            ||.|       |.:.....:.:||:||:||||.......|.|||:|:.|:::..|:.|:|    |
Zfish   324 LLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGRVP 388

  Fly   367 TTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSND 431
            |.:|      ...:|.:|..:||.||:..:.|||.|:|..||::.||.:|:||.:.:.....|.|
Zfish   389 TGED------VPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVGGYLIPKGTQLALCHYSTSMD 447

  Fly   432 DKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRL 496
            ::.|.:..||.|:||::.|.:..:         :.|..:|||:|.|:|||:||||||:...|.:|
Zfish   448 EENFPRPEEFRPDRWIRKDASDRV---------DNFGSIPFGYGIRSCIGRRIAELEMHLALTQL 503

  Fly   497 LRSYKVSWLPETPIEYESTI-ILSPCGDIRFK 527
            |:::.:...|:|...:..|. :|.|...|..:
Zfish   504 LQNFHIEVSPQTTEVHAKTHGLLCPGASINLR 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	125/483 (26%)
cyp27c1	NP_001106808.2	p450	74..517	CDD:306555	127/484 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	1	0.900	-	-		OOG6_100895
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.780