Protein Alignment Cyp12b2 and cyp27c1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 133/502 - (26%)
• Similarity: 244/502 - (48%)
• Gaps: 68/502 - (13%)

  Fly    56 IPGPS-LLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYR 119
            :|||| :..::.||...|..|...:.|.:   ...||.|:  ....|....|...:.|......|
 Frog     1 MPGPSTMANLVEFFWRDGFGRIQEIQQKH---ARQYGRIF--KSHFGPQFVVSIADKDMVAQVLR 60

  Fly   120 NEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLD 184
            .|...|.|..:||.:.||::.....     ||.|.:|::|.::|:.:...:::.::|......::
 Frog    61 AERDAPQRANMESWHEYRELRGRST-----GLISAEGEKWLNMRSVLRQKILRPRDVAMYSGGVN 120

  Fly   185 QISKEFIDKLETQRNPETHTLTTDFHNQLKM-WAFESISFVALNTRMGLLSDNPDPNADRLAKHM 248
            ::.::.:.::...|..|:..||....|.|.. ::.|:|:.:....|:|.|.       |::.:..
 Frog   121 EVVEDLVKRIRKLRVQESDGLTVTNVNDLYFKYSMEAIATILYECRLGCLD-------DQIPQQT 178

  Fly   249 RDFFNYSFQFDVQPSIWTFYKT---AG-------------FKKFLKTYDNITDITSNYIETAMRG 297
            :::      .:....:::.:||   ||             :::|.:::|.:...:..:::..:|.
 Frog   179 KEY------IEALELMFSMFKTTMYAGAIPKWLRPLIPKPWREFCRSWDGLFKFSQIHVDDRLRQ 237

  Fly   298 F------GKNDDGKTKCVLEQLL---EHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSK 353
            .      |:...|.   ||..||   |.:.:.....:.:||:||:||||.......|.||:||..
 Frog   238 IESQLEKGEEVQGG---VLTHLLLSKELDLEEIYANMTEMLLAGVDTTSFTLSWATYLLAKNPGI 299

  Fly   354 QEKLRRELLRILPTTKDSL-TDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPR 417
            ||.:.:::::..  .||.: |.::...||.:||.:||.||:..:.|||.|:|..|||:.||.:|:
 Frog   300 QEAVYQQIVQNF--GKDQVPTAEDVPKMPLVRAVVKETLRLFPVLPGNGRVTQDDLVVGGYFIPK 362

  Fly   418 GTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGK 482
            ||.:.:.....|.|.:.|..:.||.||||::|.        ...|..| |..:|||:|.|:|||:
 Frog   363 GTQLALCHYSTSYDAECFPAAEEFRPERWIRSG--------NLERKEN-FGSIPFGYGIRSCIGR 418

  Fly   483 RIAELEIETLLVRLLRSYKVSWLPETPIEYESTI-ILSPCG--DIRF 526
            |:||||:..||::||:::::...|:|......|. :|.|.|  ::||
 Frog   419 RVAELEMHLLLIQLLQNFEIKPSPQTTTVLPKTHGLLCPGGKINVRF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	122/467 (26%)
cyp27c1	NP_001011341.1	cytochrome_P450	30..462	CDD:477761	122/465 (26%)