Protein Alignment Cyp12b2 and cyp27b1

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001006907.1
• Gene: cyp27b1 / 448754
• XenbaseID: XB-GENE-942527
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 135/508 - (26%)
• Similarity: 220/508 - (43%)
• Gaps: 65/508 - (12%)

  Fly    36 LELADSR-------IDEKWQQA------------RSFGEIPGPSLLRMLSFFMPGGALRNTNLIQ 81
            |:|..||       :.|.|.:.            :|..::||||.:..:|.......|...:.:|
 Frog     5 LKLGSSRSSQLFRGLQELWAETVLKNSEKVIKGHKSLADMPGPSTVSFISDLFCRRGLARLHELQ 69

  Fly    82 MNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFK 146
            :..  :..:|.::  ....|....|....|...|...|.||..|||..|.|...||:......
 Frog    70 LEG--KAKFGPVW--KASFGPILTVHVAEPSLIEQVLRQEGKHPIRSDLSSWKDYRQCRGHSY-- 128

  Fly   147 GVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHN 211
               ||.:.:|:||...|:.:...::|.:.|......|:.:..:.|.|:..||:...:.:..|...
 Frog   129 ---GLLTAEGEEWQQFRSILGKHMLKPKEVEAYSDVLNDVVGDLIKKINYQRSQNQNNVVKDIAK 190

  Fly   212 QLKMWAFESISFVALNTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKF 276
            :..|:..|.||.|...:|:|.|........::..:.:...|..:......|..........::||
 Frog   191 EFYMFGLEGISSVLFESRIGCLEPTVPKETEKFIQSINTMFVMTLLTMAMPKFLHKIFRKPWQKF 255

  Fly   277 LKTYDNITDITSNYIETAMRGF------GKNDDGKTKCVLEQLLEHNK---KVAVTMVMDMLMAG 332
            .:::|.:......:|:..|:..      |:..:||   .|...|...|   |.....|.::|:||
 Frog   256 CESWDYMFAFAKGHIDKRMKDVAQKLAQGEKVEGK---YLTYYLAQEKIPMKSIYGNVTELLLAG 317

  Fly   333 IDTTSSACLTILYHLARNPSKQEKLRRELLRIL-----PTTKDSLTDQNTKNMPYLRACIKEGLR 392
            :||.||.....||.||::|..|..:..|:..||     |:..|      ...||.|:|.:||.||
 Frog   318 VDTISSTLSWSLYELAQHPDIQSAVYSEVEEILQGKQIPSPSD------VARMPLLKAVVKEVLR 376

  Fly   393 ITSITPGNFR-ITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQ 456
            :..:.|||.| :..:|:.:..|.:|:.|.:.:.....|.|:..|:..:||.|:||||.:
 Frog   377 LYPVIPGNARVVADRDIQVGDYIIPKKTLITLCHYATSRDENVFSNPNEFQPDRWLKKE------ 435

  Fly   457 ACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETP 509
                 .|.:|:..||||||.|:|||:||||||:...|.|:|..::|.  ||.|
 Frog   436 -----DTHHPYASLPFGFGKRSCIGRRIAELEVYLALARILSHFEVK--PEQP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	126/466 (27%)
cyp27b1	NP_001006907.1	p450	45..503	CDD:365848	128/468 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.980