Protein Alignment Cyp12b2 and sad

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 113/547 - (20%)
• Similarity: 202/547 - (36%)
• Gaps: 109/547 - (19%)

  Fly    36 LELADSRIDEKWQQARSFGEIPG---------------PSLLRMLSFFMPGGALRNTNLIQMNRL 85
            |.|..||.|....|.....|:|.               |.:..::.....|||   |:|.:....
  Fly    28 LSLFRSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGA---THLHKYIDA 89

  Fly    86 MREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGG 150
            ..:.||.|: ...:.|..:|||..:.:.....:::||.:|.....::...|.:.|...     .|
  Fly    90 RHKQYGPIF-RERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQ-----RG 148

  Fly   151 LASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTD------- 208
            |...:|.||...|..:|.:|:. .|:......::..::..:|:.: :|..|...:...
  Fly   149 LFFMEGAEWLHNRRILNRLLLN-GNLNWMDVHIESCTRRMVDQWK-RRTAEAAAIPLAESGEIRS 211

  Fly   209 -----FHNQLKMWAFESISFVALNTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQP------ 262
                 ...||..|:.|.:..:...|.: |.......:.|...:.:...|.:|.:....|
  Fly   212 YELPLLEQQLYRWSIEVLCCIMFGTSV-LTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQI 275

  Fly   263 ---SIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVL---------EQLLE 315
               .||                  .|..:|..|....|....|    .|:.         ::.|.
  Fly   276 LRLPIW------------------RDFEANVDEVLREGAAIID----HCIRVQEDQRRPHDEALY 318

  Fly   316 HNKKVA-------VTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLT 373
            |..:.|       ..:.:|:::|..|||:.:....|:.|::.|..|::|.:|
  Fly   319 HRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKE------------- 370

  Fly   374 DQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQS 438
             :.|.:...:...|||.||:..:.|...|..|:|..|.|:.:.:.|.||:.:.....|..:|.|.
  Fly   371 -RATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQP 434

  Fly   439 SEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVS 503
            ...:||||...:         ..:.......|||..|.|:|||:|:|..::.:||.|....:::|
  Fly   435 ERVLPERWCIGE---------TEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMS 490

  Fly   504 WLPETPIEYESTIILSPCGDIRFKLEP 530
            .|.|.|::....::..|...:|..|.|
  Fly   491 CLNEMPVDSVLRMVTVPDRTLRLALRP 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	96/474 (20%)
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	96/474 (20%)