Protein Alignment Cyp12b2 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 210/505 - (41%)
• Similarity: 317/505 - (62%)
• Gaps: 11/505 - (2%)

  Fly    33 QTQLELADSRIDEKWQQARSFGEIPGPSLLRM-LSFFMPGGALRNTNLIQMNRLMREMYGDIYCI 96
            ||.:..|::|.|.:|.||:.|.:||..::..: :...||||..:|..|::|...||:.||||:.:
  Fly    27 QTNVATAEAREDSEWLQAKPFEQIPRLNMWALSMKMSMPGGKYKNMELMEMFEAMRQDYGDIFFM 91

  Fly    97 PGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWAD 161
            ||:||.|..:.|:||.|||:.:|||||||.|.|..:|.|:|:.:|.|.::||.|:...||:.|.|
  Fly    92 PGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGD 156

  Fly   162 IRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVAL 226
            .|..||||||:.:|||....::.|:::||:.::...|:|:|.....||.:.:..|..||:|.|||
  Fly   157 FRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVAL 221

  Fly   227 NTRMGLL-SDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNY 290
            :.::||| :.|.:..|.:|..::.:||..|...:::||.|.:.||...|:.::..|.|.::|..|
  Fly   222 DKQLGLLKNSNKESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAY 286

  Fly   291 IETAMRGFGKN-DDG-----KTKCVLEQLLEHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLAR 349
            ::.|:....|. .:|     ..:.|||:||:.::|||..|.|||||||:|||||....:|..||:
  Fly   287 VDEAIERLDKEAKEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAK 351

  Fly   350 NPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQ 414
            ||.||.:||.|::::||......|:.:.||:|||||||||..|:..:..||.|:..:|.|||||:
  Fly   352 NPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYR 416

  Fly   415 VPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPA--ARTRNPFVYLPFGFGPR 477
            ||.||.|.:..|.....|:||.|:|||:|||||:|....: ..|||  .::.||||:||||||||
  Fly   417 VPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSE-SKCPANELKSTNPFVFLPFGFGPR 480

  Fly   478 TCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRFK 527
            .|:||||.|:|:|....||:|::.|.:...|...:.|.:|..|...::||
  Fly   481 MCVGKRIVEMELELGTARLIRNFNVEFNYPTENAFRSALINLPNIPLKFK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	189/446 (42%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	189/446 (42%)