Protein Alignment Cyp12b2 and Cyp12c1

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001287109.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 197/525 - (37%)
• Similarity: 303/525 - (57%)
• Gaps: 29/525 - (5%)

  Fly    14 SGNQLWFNRNSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTN 78
            :.:||...||......:.|          ::.:|:.|:.|.|:|||:..::...|..||......
  Fly    12 ANSQLAATRNPDASSYVQQ----------LESEWEGAKPFTELPGPTRWQLFRGFQKGGEYHQLG 66

  Fly    79 LIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPD 143
            :..:.||.::.:|||..|||:.|.|:.|||:|.:.||..||.||.||:|.|.|.:.:||...:.:
  Fly    67 MDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDE 131

  Fly   144 VFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTD 208
            .||...||..: |.||...|:.||||||:.:||...|..:.:::::|::::...|:.|:..:..|
  Fly   132 FFKNCMGLFGN-GAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRDKESQEVPGD 195

  Fly   209 FHNQLKMWAFESISFVALNTRMGLLSD-NPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAG 272
            |.|.:....|||::.|||:..:|||.: ||.|.|.:|.|::....:..|...|:||::.:..|..
  Fly   196 FMNTINHLTFESVATVALDRELGLLREANPPPEASKLFKNIEVLMDSFFDLGVRPSLYRYIPTPT 260

  Fly   273 FKKFLKTYDNITDITSNYIETAM----RGFGKNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGI 333
            :|||.:..|.|.|..|.|:..|:    |...:.|....|.||||||:.::|:||.|.|||||.|:
  Fly   261 YKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQGDSNDHKSVLEQLLQIDRKLAVVMAMDMLMGGV 325

  Fly   334 DTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITP 398
            ||||:|...||.:||:||.||::||.|:|..|.:.....|.::.|::|||||.|||.||:..:|.
  Fly   326 DTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTF 390

  Fly   399 GNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWL------KSDLAPDIQA 457
            ||.|....|:||.||::|:||.:||....|..||:.:.::.||||||||      |||:..:
  Fly   391 GNARSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMN--- 452

  Fly   458 CPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCG 522
                :..|.|:|||||||||.|:||||.:||:|..:..|:|::.:.:...|...|:...:..|..
  Fly   453 ----KDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRFLYKPNI 513

  Fly   523 DIRFK 527
            .::||
  Fly   514 PLKFK 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	182/462 (39%)
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	184/464 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445021
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	1	0.900	-	-		OOG6_100895
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	11	10.800