Protein Alignment Cyp12b2 and Cyp4d20

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 123/524 - (23%)
• Similarity: 213/524 - (40%)
• Gaps: 78/524 - (14%)

  Fly    46 KWQQARSF--GEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFT 108
            |.|:..:|  ..||||..:.:|...:....|...|:|.......:.||..:.. .::|: :.::|
  Fly    21 KRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRF-WILGE-SLIYT 83

  Fly   109 YNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKV 173
            .:...||....:..:      ||....|..: ||  |...|.|.| .|::| ..|.|:.......
  Fly    84 KDLQYFETILSSTTL------LEKGQLYEYL-RP--FLNDGLLVS-TGRKW-HARRKIFTHAFHF 137

  Fly   174 QNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPD 238
            :.:...:..:|:.|...:|.|....:.:|   ..|....:.:.|.:.|:..|:..::...:|...
  Fly   138 KVLEHYVEIMDRHSSVMVDNLRKVADGKT---AVDMLKYVSLAALDVITEAAMGVQVNAQNDPDF 199

  Fly   239 P-----------NADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGF--KKFLKTYDNITDITSNY 290
            |           ..||:       |.:|.:::     |.|...|..  ::.|.....:.|.|...
  Fly   200 PYIKALKSVVYIQPDRM-------FRFSRRYN-----WLFPLAAPLLHRQLLSDIRVMHDFTDKV 252

  Fly   291 I----ETAMR----------GFGKNDDGKTK--CVLEQLLE---HNKKVAVTMVMD----MLMAG 332
            |    ||..|          ..|..:.|...  .:|:.||:   :|:.::...:.:    .:..|
  Fly   253 ISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEG 317

  Fly   333 IDTTSSACLTILYHLARNPSKQEKLRRELLRIL-PTTKDSLTDQNTKNMPYLRACIKEGLRITSI 396
            .|||||.....||.:||:|..|:::..||.|:| |.....:|....:::.||...|||.:|:...
  Fly   318 DDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPP 382

  Fly   397 TPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAA 461
            .|...|...|:|.:....:|..|.:.:.:.....|..||.....|.|||:|:..          .
  Fly   383 VPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQ----------E 437

  Fly   462 RTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRF 526
            :..|.|.|:||..||:.|||::.|.||::.|:.::||.|::..|.| .::.....||.....|..
  Fly   438 QGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGE-ELKPMLNFILRSASGINV 501

  Fly   527 KLEP 530
            .|.|
  Fly   502 GLRP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	109/474 (23%)
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	109/471 (23%)